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https://hdl.handle.net/20.500.14094/0100486356
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2024-06-02
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0100486356 (fulltext)
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メタデータID
0100486356
アクセス権
open access
出版タイプ
Version of Record
タイトル
Relationship between residual visual field and full-field stimulus testing in patients with late-stage retinal degenerative diseases
著者
Sakai, Daiki ; Maeda, Tadao ; Yamamoto, Midori ; Yokota, Satoshi ; Maeda, Akiko ; Hirami, Yasuhiko ; Nakamura, Makoto ; Kurimoto, Yasuo ; Mandai, Michiko
著者名
Sakai, Daiki
著者名
Maeda, Tadao
著者名
Yamamoto, Midori
著者名
Yokota, Satoshi
著者名
Maeda, Akiko
著者名
Hirami, Yasuhiko
著者ID
A0882
研究者ID
1000080273788
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=82142348522a81ad520e17560c007669
著者名
Nakamura, Makoto
中村, 誠
ナカムラ, マコト
所属機関名
医学研究科
著者名
Kurimoto, Yasuo
著者名
Mandai, Michiko
収録物名
Scientific Reports
巻(号)
14(1)
ページ
2793
出版者
Nature Portfolio
刊行日
2024-02-02
公開日
2024-02-27
抄録
This study aimed to investigate how the extent and central/peripheral location of the residual visual field (VF) in patients with late-stage inherited retinal diseases (IRDs) are related to retinal sensitivity detected using full-field stimulus testing (FST). We reviewed the results of Goldmann perimetry and FST from the medical records of patients with IRDs whose VF represents central (within 10°) and/or peripheral islands, or undetectable. In total, 19 patients (19 eyes) were analyzed in this study. The median value of residual VF area was 1.38%. The median values of rod and cone sensitivities were − 14.9 dB and 7.4 dB, respectively. Patients with only the peripheral island (− 33.9 dB) had better median rod sensitivity than other groups (only central, − 18.9 dB; both, − 3.6 dB). VF area significantly correlated with rod sensitivity (r = − 0.943, p = 0.005) in patients with only peripheral island, but not with cone sensitivity. Peripheral VF islands were significant contributors to FST results, especially rod sensitivity. With reduced or loss of central vision, the extent of residual peripheral VF significantly affected rod sensitivity, suggesting that FST can be useful in quantitatively estimating the overall remaining vision in patients with late-stage IRD.
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医学研究科
学術雑誌論文
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© The Author(s) 2024
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
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資源タイプ
journal article
言語
English (英語)
eISSN
2045-2322
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関連情報
DOI
https://doi.org/10.1038/s41598-024-53474-6
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