Human In-vivo MR Current Density Imaging (MRCDI) Based on Optimized Multi-echo 
Spin Echo (MESE)

Göksu, C; Ganson, L; Ehses, P; Scheffler, K; Thielscher, A

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Human In-vivo MR Current Density Imaging (MRCDI) Based on Optimized Multi-echo Spin Echo (MESE)

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Göksu, C
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Ehses, P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler, K
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Thielscher, A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zitation

Göksu, C., Ganson, L., Ehses, P., Scheffler, K., & Thielscher, A. (2017). Human In-vivo MR Current Density Imaging (MRCDI) Based on Optimized Multi-echo Spin Echo (MESE). Poster presented at 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.

Zitierlink: https://hdl.handle.net/21.11116/0000-0000-C4C5-4

Zusammenfassung

MRCDI aims at imaging an externally injected current flow in the human body, and might be useful for many biomedical applications. However, the method requires very sensitive measurement of the current-induced magnetic field component ?Bz,c parallel to main field. We systematically optimized MESE to determine its most efficient parameters. In one of the first human in-vivo applications of MRCDI, the optimized sequence was successfully used to image the ?Bz,c distribution in the brain caused by a two-electrode montage, as confirmed by finite-element calculations of ?Bz,c. Further improvements will be performed to increase its robustness to field drifts.