Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating 
hypoblast, vasculature, and in multiple embryonic epithelia

Tucker, B.; Hepperle, C.; Kortschak, D.; Rainbird, B.; Wells, S.; Oates, Andrew C.; Lardelli, M.

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia

MPS-Authors

/persons/resource/persons219499

Oates, Andrew C.
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Tucker, B., Hepperle, C., Kortschak, D., Rainbird, B., Wells, S., Oates, A. C., & Lardelli, M. (2007). Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia. Gene Expression Patterns, 7(3), 258-265.

引用: https://hdl.handle.net/21.11116/0000-0001-0FCF-7

要旨

The human gene AGTRL1 is an angiotensin II receptor-like gene expressed in vasculature, which acts as the receptor for the small peptide APELIN, and a co-receptor for Human Immunodeficiency Virus. Mammalian AGTRL1 has been shown to modulate cardiac contractility, venous and arterial dilation, and endothelial cell migration in vitro, but no role in the development of the vasculature, or other tissues, has been described. We report the identification and expression of the zebrafish ortholog of the human gene AGTRL1. Zebrafish agtrl1a is first expressed before epiboly in dorsal precursors. During epiboly it is expressed in the enveloping layer, yolk syncytial layer and migrating mesendoderm. During segmentation stages, expression is observed in epithelial structures such as adaxial cells, border cells of the newly formed somites, developing lens, otic vesicles and venous vasculature.