Breathing Gas Calibration for MR CMRO2 Measurements: Comparative Effects on 
Functional Brain Networks

Ivanov, D; Lohmann, G; Kabisch, S; Henseler, I; Schloegl , H; Heinke, W; Hutton, C; Turner, R

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Breathing Gas Calibration for MR CMRO2 Measurements: Comparative Effects on Functional Brain Networks

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https://cds.ismrm.org/protected/11MProceedings/files/1_program.htm
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Ivanov, D., Lohmann, G., Kabisch, S., Henseler, I., Schloegl, H., Heinke, W., et al. (2011). Breathing Gas Calibration for MR CMRO2 Measurements: Comparative Effects on Functional Brain Networks. In 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011).

Cite as: https://hdl.handle.net/21.11116/0000-0002-4F4E-0

Abstract

Regional changes in the cerebral metabolic rate of oxygen (CMRO2) associated with neural activation can be estimated with MRI using the deoxyhaemoglobin dilution model, whose application requires the calibration of resting-state BOLD signal with a gaseous challenge. In this study we used eigenvector centrality mapping (ECM) to assess whether the brain network connectivity is influenced by commonly used calibration gases. The results suggest that these functional brain networks are only slightly modulated, confirming the applicability of the CMRO2 mapping methodology across most of the brain.