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Model systems for regeneration: planarians.

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Thommen,  Albert
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Grohme,  Markus
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

/cone/persons/resource/persons232159

Vila-Farré,  Miquel
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Werner,  Steffen
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

/cone/persons/resource/persons219585

Rink,  Jochen
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Ivankovic, M., Haneckova, R., Thommen, A., Grohme, M., Vila-Farré, M., Werner, S., et al. (2019). Model systems for regeneration: planarians. Development (Cambridge, England), 146(17): dev167684. doi:10.1242/dev.167684.


Cite as: https://hdl.handle.net/21.11116/0000-0006-7DE2-F
Abstract
Planarians are a group of flatworms. Some planarian species have remarkable regenerative abilities, which involve abundant pluripotent adult stem cells. This makes these worms a powerful model system for understanding the molecular and evolutionary underpinnings of regeneration. By providing a succinct overview of planarian taxonomy, anatomy, available tools and the molecular orchestration of regeneration, this Primer aims to showcase both the unique assets and the questions that can be addressed with this model system.