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Tissue Mapping in Brain Tumors with Partial Volume Magnetic Resonance Fingerprinting (PV-MRF)

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Deshmane, A., Badve, C., Rogers, M., Yu, A., Ma, D., Sunshine, J., et al. (2015). Tissue Mapping in Brain Tumors with Partial Volume Magnetic Resonance Fingerprinting (PV-MRF). Poster presented at 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, ON, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-0006-9AD3-E
Abstract
Magnetic resonance fingerprinting (MRF) can be used to simultaneously map T1, T2 and off-resonance. It was previously demonstrated that modeling single voxel MRF signals as a weighted sum of evolutions from known tissue types can be used to quantify subvoxel tissue fractions in the brain and perform tissue segmentation. Here MRF is used to estimate fractions of free fluid, intra/extracellular water, and myelin water in brain tumor patients with glioblastoma multiforme and metastases. A significant difference in free fluid and intra/extracellular water fraction was found in perilesional white matter between the two patient groups.