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Phosphorus metabolic images of the human brain at 9.4 T using Chemical Shift Imaging: Investigation of differences in grey and white matter tissue

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Ruhm,  L
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Dorst,  J
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons133464

Avdievich,  NI
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84402

Henning,  A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Ruhm, L., Dorst, J., Avdievich, N., & Henning, A. (2020). Phosphorus metabolic images of the human brain at 9.4 T using Chemical Shift Imaging: Investigation of differences in grey and white matter tissue. In 2020 ISMRM & SMRT Virtual Conference & Exhibition (pp. 196-197).


Cite as: https://hdl.handle.net/21.11116/0000-0006-D7B5-B
Abstract
31P Magnetic Resonance Spectroscopic Imaging (MRSI) is a non-invasive method that can reveal information about the energy and phospholipid metabolism. In this work, we investigate the differences in signal amplitudes of different 31P metabolites between grey and white matter tissue in the human brain. We acquired highly resolved 31P MRSI data at an ultrahigh field strength B0 of 9.4 T from the brain of six healthy volunteers. For the quantification of the 31P MRSI data, different correction were applied to the signal amplitudes.