Over-discretized reconstruction to correct for B0 inhomogeneity and improve 
localization in 1H-MRSI of the prostate

Tenbergen, C; Ruhm, L; Heerschap, A; Henning, A; Scheenen, T

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Over-discretized reconstruction to correct for B0 inhomogeneity and improve localization in 1H-MRSI of the prostate

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Ruhm, L
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Henning, A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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https://www.ismrm.org/20/program_files/DP06-02.htm
(Abstract)

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Citation

Tenbergen, C., Ruhm, L., Heerschap, A., Henning, A., & Scheenen, T. (2020). Over-discretized reconstruction to correct for B0 inhomogeneity and improve localization in 1H-MRSI of the prostate. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.

Cite as: https://hdl.handle.net/21.11116/0000-0006-D8DB-0

Abstract

n in vivo MRSI spatial inhomogeneities of the main magnetic field cause spectral line broadening and location dependent frequency shifts in the spectra. An over-discretized reconstruction method is applied to existing prostate 1H-MRSI data, consisting of spatial over-discretization of the MRSI grid, frequency shift correction according to a high resolution B0map and weighted spatial averaging to the target resolution. Intravoxel B0 variations are corrected for and resampling to a new target resolution results in improved localization of signals. This could lead to detection of signals with lower spectral intensity and to improved visualization of smaller cancer lesions in the prostate.