English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Circular dichroism as a detection method in the screening of enantioselective catalysts

MPS-Authors
/persons/resource/persons58919

Reetz,  Manfred T.
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

Kühling,  Klaus M.
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58623

Hinrichs,  Heike
Research Department Maier, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58504

Deege,  Alfred
Research Department Maier, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Reetz, M. T., Kühling, K. M., Hinrichs, H., & Deege, A. (2000). Circular dichroism as a detection method in the screening of enantioselective catalysts. Chirality, 12(5-6), 479-482. doi:10.1002/(sici)1520-636x(2000)12:5/6<479:aid-chir32>3.0.co;2-#.


Cite as: https://hdl.handle.net/21.11116/0000-0008-9116-B
Abstract
The combination of liquid chromatography (HPLC), UV/Vis-spectroscopy and circular dichroism (CD) can be used to construct a high-throughput screening system to determine the enantioselectivity of enzyme- or metal-catalyzed reduction of acetophenone with formation of (S)- and (R)-1-phenylethanol. Prerequisite for the viability of this system is the experimental finding that the anisotropy factor g is linearly related to the enantiomeric excess (ee) and that it is independent of concentration, thereby excluding possible aggregation effects.