Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
Zur Ablage hinzufügen
  Lokale TagsFreigabegeschichteDetailsÜbersicht

Freigegeben
Zeitschriftenartikel

Intracellular regulation of the insect chemoreceptor complex impacts odour localization in flying insects

MPG-Autoren
/persons/resource/persons37472

Getahun,  Merid Negash
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;
IMPRS on Ecological Interactions, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons134353

Thoma,  Michael
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;
IMPRS on Ecological Interactions, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons37475

Lavista Llanos,  Sofia
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons139902

Keesey,  Ian
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons3971

Knaden,  Markus
Research Group Dr. M. Knaden, Insect Behavior, Department of Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons4251

Wicher,  Dieter
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons4075

Olsson,  Shannon B.
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;

/persons/resource/persons3909

Hansson,  Bill S.
Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society;

Externe Ressourcen

http://dx.doi.org/10.1242/jeb.143396
(Verlagsversion)

Volltexte (beschränkter Zugriff)
Für Ihren IP-Bereich sind aktuell keine Volltexte freigegeben.
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte in PuRe verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Getahun, M. N., Thoma, M., Lavista Llanos, S., Keesey, I., Fandino, R. A., Knaden, M., et al. (2016). Intracellular regulation of the insect chemoreceptor complex impacts odour localization in flying insects. Journal of Experimental Biology, 219, 3428-3438. doi:10.1242/jeb.143396.


Zitierlink: https://hdl.handle.net/11858/00-001M-0000-002B-2E66-B
Zusammenfassung
Flying insects are well known for airborne odour tracking and have evolved diverse chemoreceptors. While ionotropic receptors (IRs) are
found across protostomes, insect odorant receptors (ORs) have only
been identified in winged insects. We therefore hypothesized that the
unique signal transduction of ORs offers an advantage for odour
localization in flight. Using Drosophila, we found expression and
increased activity of the intracellular signalling protein PKC in antennal
sensilla following odour stimulation. Odour stimulation also enhanced
phosphorylation of theORco-receptorOrco in vitro, while site-directed
mutation of Orco or mutations in PKC subtypes reduced the sensitivity
and dynamic range of OR-expressing neurons in vivo, but not
IR-expressing neurons. We ultimately show that these mutations
reduce competence for odour localization of flies in flight.We conclude
that intracellular regulation of OR sensitivity is necessary for efficient
odour localization, which suggests a mechanistic advantage for the
evolution of the OR complex in flying insects.