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Spatial and temporal patterns of Krüppel gene expression in early Drosophila embryos

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Knipple,  DC
Department Biochemistry, Max Planck Institute for Developmental Biology, Max Planck Society;

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Seifert,  E
Department Biochemistry, Max Planck Institute for Developmental Biology, Max Planck Society;

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Rosenberg,  UB
Department Biochemistry, Max Planck Institute for Developmental Biology, Max Planck Society;

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Preiss,  A
Department Biochemistry, Max Planck Institute for Developmental Biology, Max Planck Society;

/persons/resource/persons15265

Jäckle,  H
Department Biochemistry, Max Planck Institute for Developmental Biology, Max Planck Society;

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Citation

Knipple, D., Seifert, E., Rosenberg, U., Preiss, A., & Jäckle, H. (1985). Spatial and temporal patterns of Krüppel gene expression in early Drosophila embryos. Nature, 317(6032), 40-44. doi:10.1038/317040a0.


Cite as: https://hdl.handle.net/21.11116/0000-000C-06A9-F
Abstract
The Krüppel (Kr) locus is a member of the 'gap' class of segmentation genes of Drosophila melanogaster. Mutations at the Kr locus cause the deletion of contiguous segments from the embryonic body pattern. We have elucidated the spatial and temporal characteristics of Kr gene expression during early embryo development, the localization of cytoplasmic Kr+ activity and its spatial requirement for normal segmentation.