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Genome-Wide Association Mapping in Arabidopsis Thaliana

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/persons/resource/persons274196

Clark,  RM
Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society;

/persons/resource/persons85266

Weigel,  D       
Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society;

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https://www.arabidopsis.org/news/19th_ICAR_AbstractBook_2008.pdf
(Abstract)

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Citation

Vilhjalmsson, B., Atwell, S., Willems, G., Huang, Y., Jiang, R., Li, Y., et al. (2008). Genome-Wide Association Mapping in Arabidopsis Thaliana. Poster presented at 19th International Conference on Arabidopsis Research (ICAR 2008), Montreal, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-000C-B2E8-5
Abstract
Recent advances in genotyping technology have made large scale genome-wide association studies feasible. The small genome size, range of linkage disequilibrium, selfing nature, and reproducibility of phenotypes make A. thaliana an excellent subject for such studies. Here we present a GWA study with a number of phenotypes related to flowering and disease resistance, and 192 A. thaliana accessions from a global sample, genotyped using a 250k Affymetrix SNP chip. Several association methods were applied to the data, both haplotype based and single-SNP methods. Confounding population structure continues to be a problem, underscoring the importance of controlling for it.