Petherick_Respiratory Medicine manuscript main document accepted version.pdf (259.99 kB)
Ethnic and socio-economic differences in the prevalence of wheeze, severe wheeze, asthma, eczema and medication usage at 4 years of age: Findings from the born in Bradford birth cohort
journal contribution
posted on 2017-03-31, 13:39 authored by Emily PetherickEmily Petherick, Neil Pearce, Jordi Sunyer, John WrightBackground
Asthma, wheeze and eczema are common in early childhood and cause considerable morbidity. Generally rates of these conditions are higher in high income compared to low income countries. Rates in developed nations are generally higher than in less developed countries. After migration to Western countries, differences in risks of developing these conditions may between migrant and non-migrant may diminish.
Methods
A convenience sample of 1648 children of White British, Pakistani or Other ethnicity aged between 4 and 5 years were recruited from the main Born in Bradford cohort. Children’s parents or guardians were asked to report on a range of potential risk factors and their associations with wheeze, asthma and eczema. Relationships between ethnicity and disease outcomes were examined using logistic regression after adjustment for other relevant risk factors and confounders.
Results
Ethnic differences in doctor diagnosed asthma were evident, with children of Other ethnic origin being less likely and children of Pakistani origin more likely to have a diagnosis than White British children, even after adjustment for other risk factors this difference only remained significant for the Other ethnic group. Ethnic differences were not observed in other outcomes including wheeze in the past 12 months, severe wheeze and taking medications for breathing problems.
Conclusions
In UK born children, traditional risk factors such as gender, family history, socio-economic status and child’s medical history may be stronger risk factors than ethnicity or familial migration patterns.
Funding
The data collection for this study was funded by the MeDALL project. MeDALL is a collaborative project funded by the Health Cooperation Work Programme of the 7th Framework programme (grant agreement No. 261357).
History
School
- Sport, Exercise and Health Sciences
Published in
Respiratory MedicineCitation
PETHERICK, E.S. ...et al., 2016. Ethnic and socio-economic differences in the prevalence of wheeze, severe wheeze, asthma, eczema and medication usage at 4 years of age: Findings from the born in Bradford birth cohort. Respiratory Medicine, 119, pp. 122–129.Publisher
© ElsevierVersion
- AM (Accepted Manuscript)
Publisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/Acceptance date
2016-08-22Publication date
2016-08-22Notes
This paper was accepted for publication in the journal Respiratory Medicine and the definitive published version is available at http://dx.doi.org/10.1016/j.rmed.2016.08.017ISSN
1532-3064Publisher version
Language
- en