Physical Fitness and Mitochondrial Respiratory Capacity in Horse Skeletal Muscle

Horse; muscle; mitochondria; Fitness; performance; high-resolution respirometry; Cheval; mitochondrie; Condition physique; respirométrie haute résolution; oxygraphie; oxymétrie

Abstract :

[en] We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0–2.5 mg) permeabilized muscle fibres sampled from triceps brachii of healthy horses. The present investigation on horse skeletal muscle has tested the methodology used to study mitochondrial function in muscle microbiopsies by high-resolution respirometry to define reference protocols for horses (from sampling procedure to data analysis).
[fr] Nous avons appliqué la respirométrie à haute résolution et mis au point des protocoles de titration pour étudier la physiologie mitochondriale dans des microbiopsies musculaires prélevées au niveau du triceps brachial de chevaux sains. Ces études ont pour objet de valider la méthodologie et de définir des protocoles de référence pour les chevaux.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Votion, Dominique ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux

Gnaiger, Erich

Lemieux, Hélène

Mouithys-Mickalad, Ange ; Université de Liège - ULiège > Centre de l'oxygène : Recherche et développement (C.O.R.D.)

Serteyn, Didier ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux

Language :

English

Title :

Physical Fitness and Mitochondrial Respiratory Capacity in Horse Skeletal Muscle

Alternative titles :

[fr] Condition physique et capacité respiratoire mitochondriale dans le muscle squelettique de cheval

Publication date :

18 April 2012

Journal title :

PLoS ONE

eISSN :

1932-6203

Publisher :

Public Library of Science, San Franscisco, United States - California

Volume :

Issue :

Pages :

1-12

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034890

Funders :

DGA - Région wallonne. Direction générale de l'Agriculture [BE]

Available on ORBi :

since 20 April 2012

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