Nuclear Medicine techniques in transplantation

LOVINFOSSE, Pierre; HUSTINX, Roland

doi:10.1007/s40336-016-0216-5

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Nuclear Medicine techniques in transplantation

LOVINFOSSE, Pierre; HUSTINX, Roland

2017 • In Clinical and Translational Imaging

Peer reviewed

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https://hdl.handle.net/2268/205276

DOI
10.1007/s40336-016-0216-5

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Keywords :

Scintigraphy; PET/CT; Transplantation

Abstract :

[en] Organ transplantation has grown over the past decades thanks to major improvements in surgical techniques and immunosuppressive treatment. Nuclear medicine is used for non-invasively improving the selection of candidates to give or receive a transplant, for monitoring graft recipients and for diagnosing and managing early and late complications. This review describes the clinical role of nuclear medicine in transplantation and discusses some of the possible perspectives.

Disciplines :

Surgery
Gastroenterology & hepatology
Radiology, nuclear medicine & imaging
Human health sciences: Multidisciplinary, general & others
Urology & nephrology
Cardiovascular & respiratory systems

Author, co-author :

LOVINFOSSE, Pierre ; Centre Hospitalier Universitaire de Liège - CHU > Service médical de médecine nucléaire et imagerie onco

HUSTINX, Roland ; Centre Hospitalier Universitaire de Liège - CHU > Service médical de médecine nucléaire et imagerie onco

Language :

English

Title :

Nuclear Medicine techniques in transplantation

Publication date :

2017

Journal title :

Clinical and Translational Imaging

ISSN :

2281-5872

eISSN :

2281-7565

Publisher :

Springer, Italy

Peer reviewed :

Peer reviewed

Available on ORBi :

since 13 January 2017

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76 (17 by ULiège)

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5 (5 by ULiège)

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Bibliography

Tonelli M, Wiebe N, Knoll G, Bello A, Browne S, Jadhav D et al (2011) Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant 11(10):2093–2109
Vincenti F, Rostaing L, Grinyo J, Rice K, Steinberg S, Gaite L et al (2016) Belatacept and long-term outcomes in kidney transplantation. N Engl J Med 374(4):333–343
Hilson AJ, Maisey MN, Brown CB, Ogg CS, Bewick MS (1978) Dynamic renal transplant imaging with Tc-99 m DTPA (Sn) supplemented by a transplant perfusion index in the management of renal transplants. J Nucl Med 19(9):994–1000
Kirchner PT, Goldman MH, Leapman SB, Kiepfer RF (1978) Clinical application of the kidney to aortic blood flow index (K/A ratio). Contrib Nephrol 11:120–126
Preston DF, Luke RG (1979) Radionuclide evaluation of renal transplants. J Nucl Med 20(10):1095–1097
Rutland MD (1985) A comprehensive analysis of renal DTPA studies. II. Renal transplant evaluation. Nucl Med Commun 6(1):21–30
Schmidlin P, Clorius JH, Lubosch EM, Siems H, Boehm M, Dreikorn K (1985) Renal perfusion and mean vascular transit time. Eur J Nucl Med 11(2–3):69–72
Anaise D, Oster ZH, Atkins HL, Arnold AN, Weis S, Waltzer WC et al (1986) Cortex perfusion index: a sensitive detector of acute rejection crisis in transplanted kidneys. J Nucl Med 27(11):1697–1701
Gedroyc W, Taube D, Fogleman I, Neild G, Cameron S, Maisey M (1986) Tc-99 m DTPA scans in renal allograft rejection and cyclosporine nephrotoxicity. Transplantation 42(5):494–497
Ash J, DeSouza M, Peters M, Wilmot D, Hausen D, Gilday D (1990) Quantitative assessment of blood flow in pediatric recipients of renal transplants. J Nucl Med 31(5):580–585
Groothedde RT, Koppejan LJ, Heidendal GK, Hasman A (1990) The differential ratio. A method for describing blood flow in renal transplants. Nucl Med Commun 11(11):771–776
al-Nahhas AM, Kedar R, Morgan SH, Landells WN, al-Murrani B, Heary T et al (1993) Cellular versus vascular rejection in transplant kidneys. Correlation of radionuclide and Doppler studies with histology. Nucl Med Commun 14(9):761–765
Chaiwatanarat T, Laorpatanaskul S, Poshyachinda M, Boonvisut S, Buachum V, Krisanachinda A et al (1994) Deconvolution analysis of renal blood flow: evaluation of postrenal transplant complications. J Nucl Med 35(11):1792–1796
Li Y, Russell CD, Palmer-Lawrence J, Dubovsky EV (1994) Quantitation of renal parenchymal retention of technetium-99m-MAG3 in renal transplants. J Nucl Med 35(5):846–850
Mizuiri S, Hayashi I, Takano M, Ban R, Ohara T, Sasaki Y et al (1994) Fractional mean transit time in transplanted kidneys studied by technetium-99m-DTPA: comparison of clinical and biopsy findings. J Nucl Med 35(1):84–89
Riedinger-Berriolo A, Touzery C, Chevet D, Toubeau M, Riedinger JM, Mezeray C et al (1994) Normal range of [99mTc]MAG-3 renogram parameters in renal transplant recipients. Transplant Proc. 26(1):301–302
Oriuchi N, Miyamoto K, Hoshino K, Imai J, Takahashi Y, Sakai S et al (1997) 99Tcm-MAG3: a sensitive indicator for evaluating perfusion and rejection of renal transplants. Nucl Med Commun 18(5):400–404
El-Maghraby TA, de Fijter JW, van Eck-Smit BL, Zwinderman AH, El-Haddad SI, Pauwels EK (1998) Renographic indices for evaluation of changes in graft function. Eur J Nucl Med 25(11):1575–1586
Lin E, Alavi A (1998) Significance of early tubular extraction in the first minute of Tc-99m MAG3 renal transplant scintigraphy. Clin Nucl Med 23(4):217–222
Dubovsky EV, Russell CD, Bischof-Delaloye A, Bubeck B, Chaiwatanarat T, Hilson AJ et al (1999) Report of the Radionuclides in Nephrourology Committee for evaluation of transplanted kidney (review of techniques). Semin Nucl Med 29(2):175–188
Heaf JG, Iversen J (2000) Uses and limitations of renal scintigraphy in renal transplantation monitoring. Eur J Nucl Med 27(7):871–879
Koizumi K, Kakiuchi H, Saguchi T, Inoue S, Fuse S, Kawakami E et al (2001) A simple objective parameter for perfusion study of renal transplant. Ann Nucl Med 15(1):27–32
Aktas A, Karakayali H, Bilgin N, Akkoc H, Moray G, Emiroglu R (2002) Serial radionuclide imaging in acute renal allograft dysfunction. Transplant Proc. 34(6):2102–2105
Aktas A (2014) Transplanted kidney function evaluation. Semin Nucl Med 44(2):129–145
Gupta SK, Lewis G, Rogers KM, Attia J, Rostron K, O’Neill L et al (2014) Quantitative (99m)Tc DTPA renal transplant scintigraphic parameters: assessment of interobserver agreement and correlation with graft pathologies. Am J Nucl Med Mol Imaging. 4(3):213–224
George EA, Codd JE, Newton WT, Haibach H, Donati RM (1976) Comparative evaluation of renal transplant rejection with radioiodinated fibrinogen 99mTc-sulfur collid, and 67Ga-citrate. J Nucl Med 17(3):175–180
Einollahi B, Bakhtiari P, Simforoosh N, Amirjalali R, Bassiri A, Nafar M et al (2005) Renal allograft accumulation of technetium-99m sulfur colloid as a predictor of graft rejection. Transplant Proc. 37(7):2973–2975
Haas M, Sis B, Racusen LC, Solez K, Glotz D, Colvin RB et al (2014) Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions. Am J Transplant 14(2):272–283
Lopes de Souza SA, Barbosa da Fonseca LM, Torres Goncalves R, Salomao Pontes D, Holzer TJ, Proenca Martins FP et al (2004) Diagnosis of renal allograft rejection and acute tubular necrosis by 99mTc-mononuclear leukocyte imaging. Transplant Proc. 36(10):2997–3001
Martins FP, Souza SA, Goncalves RT, Fonseca LM, Gutfilen B (2004) Preliminary results of [99mTc]OKT3 scintigraphy to evaluate acute rejection in renal transplants. Transplant Proc 36(9):2664–2667
Lovinfosse P, Weekers L, Bonvoisin C, Bovy C, Grosch S, Krzesinski JM et al (2016) Fluorodeoxyglucose F(18) positron emission tomography coupled with computed tomography in suspected acute renal allograft rejection. Am J Transplant 16(1):310–316
Jadoul A, Lovinfosse P, Weekers L, Delanaye P, Krzesinski JM, Hustinx R et al. (2016) The Uptake of 18F-FDG by renal allograft in kidney transplant recipients is not influenced by renal function. Clin Nuclear Med (Ahead of print)
Spicer ST, Chi KK, Nankivell BJ, Larcos G, Farlow DC, Choong KK et al (1999) Mercaptoacetyltriglycine diuretic renography and output efficiency measurement in renal transplant patients. Eur J Nucl Med 26(2):152–154
Gottlieb RH, Voci SL, Cholewinski SP, Robinette WB, Rubens DJ, O’Mara RE et al (1999) Urine leaks in renal transplant patients. Diagnostic usefulness of sonography and renography. Clin Imaging 23(1):35–39
Cohney S, Kanellis J, Howell M, Cari (2010) The CARI guidelines. Donor renal function. Nephrology (Carlton) 15(Suppl 1):S137–S145
Andrews PA, Burnapp L, Manas D, Bradley JA, Dudley C, British Transplantation S et al (2012) Summary of the British Transplantation Society/Renal Association UK guidelines for living donor kidney transplantation. Transplantation 93(7):666–673
Weinberger S, Bader M, Scheurig-Munkler C, Hinz S, Neymeyer J, Miller K et al (2014) Optimizing evaluation of split renal function in a living kidney donor using scintigraphy and calculation of the geometric mean: a case report. Case Rep Nephrol Urol 4(1):1–4
Cosgriff P, Brown H (1990) Influence of kidney depth on the renographic estimation of relative renal function. J Nucl Med 31(9):1576–1577
Akaki S, Mitsumori A, Kanazawa S, Togami I, Takeda Y, Joja I et al (1998) Technetium-99m-DTPA-galactosyl human serum albumin liver scintigraphy evaluation of regional CT/MRI attenuation/signal intensity differences. J Nucl Med 39(3):529–532
Sawamura T, Kawasato S, Shiozaki Y, Sameshima Y, Nakada H, Tashiro Y (1981) Decrease of a hepatic binding protein specific for asialoglycoproteins with accumulation of serum asialoglycoproteins in galactosamine-treated rats. Gastroenterology 81(3):527–533
Kwon AH, Ha-Kawa SK, Uetsuji S, Kamiyama Y, Tanaka Y (1995) Use of technetium 99m diethylenetriamine-pentaacetic acid-galactosyl-human serum albumin liver scintigraphy in the evaluation of preoperative and postoperative hepatic functional reserve for hepatectomy. Surgery 117(4):429–434
Kokudo N, Vera DR, Makuuchi M (2003) Clinical application of TcGSA. Nucl Med Biol 30(8):845–849
Miki K, Kubota K, Inoue Y, Vera DR, Makuuchi M (2001) Receptor measurements via Tc-GSA kinetic modeling are proportional to functional hepatocellular mass. J Nucl Med 42(5):733–737
de Graaf W, Bennink RJ, Vetelainen R, van Gulik TM (2010) Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation. J Nucl Med 51(5):742–752
Iida T, Yagi S, Hori T, Uemoto S (2015) Significance of (99m)Tc-GSA liver scintigraphy in liver surgery and transplantation. Ann Transl Med 3(2):16
Wu J, Ishikawa N, Takeda T, Tanaka Y, Pan XQ, Sato M et al (1995) The functional hepatic volume assessed by 99mTc-GSA hepatic scintigraphy. Ann Nucl Med 9(4):229–235
Satoh K, Yamamoto Y, Nishiyama Y, Wakabayashi H, Ohkawa M (2003) 99mTc-GSA liver dynamic SPECT for the preoperative assessment of hepatectomy. Ann Nucl Med 17(1):61–67
Sugai Y, Komatani A, Hosoya T, Yamaguchi K (2000) Response to percutaneous transhepatic portal embolization: new proposed parameters by 99mTc-GSA SPECT and their usefulness in prognostic estimation after hepatectomy. J Nucl Med 41(3):421–425
Kita Y, Miki K, Hirao S, Inoue Y, Ohtake T, Matsukura A et al (1998) Liver allograft functional reserve estimated by total asialoglycoprotein receptor amount using Tc-GSA liver scintigraphy. Transplant Proc 30(7):3277–3278
Sakahara H, Kiuchi T, Nishizawa S, Saga T, Nakamoto Y, Sato N et al (1999) Asialoglycoprotein receptor scintigraphy in evaluation of auxiliary partial orthotopic liver transplantation. J Nucl Med 40(9):1463–1467
Yoshizumi T, Taketomi A, Uchiyama H, Harada N, Kayashima H, Yamashita Y et al (2008) Graft size, donor age, and patient status are the indicators of early graft function after living donor liver transplantation. Liver Transpl 14(7):1007–1013
Iida T, Isaji S, Yagi S, Hori T, Taniguchi K, Ohsawa I et al (2009) Assessment of liver graft function and regeneration by galactosyl-human serum albumin (99mTc-GSA) liver scintigraphy in adult living-donor liver transplantation. Clin Transplant 23(2):271–277
Kaibori M, Kariya S, Matsui K, Ishizaki M, Ikeda H, Nakahashi Y et al (2014) Detection of Portal Vein Stenosis by Technetium-99m-Diethylenetriaminepentaacetic Acid-Galactosyl Human Serum Albumin Liver Scintigraphy after Living-Donor Liver Transplantation. Hepatogastroenterology 61(132):1063–1067
Kwon AH, Matsui Y, Kaibori M, Satoi S, Kamiyama Y (2004) Safety of hepatectomy for living donors as evaluated using asialoscintigraphy. Transplant Proc 36(8):2239–2242
Kaibori M, Ha-Kawa SK, Uchida Y, Ishizaki M, Saito T, Matsui K et al (2008) Liver regeneration in donors evaluated by Tc-99m-GSA scintigraphy after living donor liver transplantation. Dig Dis Sci 53(3):850–855
Haubner R, Vera DR, Farshchi-Heydari S, Helbok A, Rangger C, Putzer D et al (2013) Development of (6)(8)Ga-labelled DTPA galactosyl human serum albumin for liver function imaging. Eur J Nucl Med Mol Imaging 40(8):1245–1255
Ziessman HA (2014) Hepatobiliary scintigraphy in 2014. J Nucl Med Technol 42(4):249–259
Gambhir SS, Hawkins RA, Huang SC, Hall TR, Busuttil RW, Phelps ME (1989) Tracer kinetic modeling approaches for the quantification of hepatic function with technetium-99 m DISIDA and scintigraphy. J Nucl Med 30(9):1507–1518
Heyman S (1994) Hepatobiliary scintigraphy as a liver function test. J Nucl Med 35(3):436–437
Loken MK, Ascher NL, Boudreau RJ, Najarian JS (1986) Scintigraphic evaluation of liver transplant function. J Nucl Med 27(4):451–459
Engeler CM, Kuni CC, Nakhleh R, Engeler CE, duCret RP, Boudreau RJ (1992) Liver transplant rejection and cholestasis: comparison of technetium 99 m-diisopropyl iminodiacetic acid hepatobiliary imaging with liver biopsy. Eur J Nucl Med 19(10):865–870
Brunot B, Petras S, Germain P, Vinee P, Constantinesco A (1994) Biopsy and quantitative hepatobiliary scintigraphy in the evaluation of liver transplantation. J Nucl Med 35(8):1321–1327
Kaxiras A, Yamamoto S, Soderdahl G, Wernerson A, Axelsson R, Ericzon BG (2014) Cyclosporin A, but not tacrolimus, negatively affects the hepatic extraction fraction of hepatobiliary scintigraphy in liver transplant recipients. EJNMMI Res 4(1):73
Kansoul HA, Axelsson R, Yamamoto S, Savicheva I, Aspelin P, Ericzon BG et al (2007) Parameters obtained by hepatobiliary scintigraphy have significant correlation with biochemical factors early after liver transplantation. Acta Radiol 48(6):597–604
Kim JS, Moon DH, Lee SG, Lee YJ, Park KM, Hwang S et al (2002) The usefulness of hepatobiliary scintigraphy in the diagnosis of complications after adult-to-adult living donor liver transplantation. Eur J Nucl Med Mol Imaging 29(4):473–479
Aktas A, Koyuncu A, Yalcin H (2004) Acceleration of hepatobiliary dynamics in liver transplant donors. Transplant Proc 36(1):206–209
Seehofer D, Eurich D, Veltzke-Schlieker W, Neuhaus P (2013) Biliary complications after liver transplantation: old problems and new challenges. Am J Transplant 13(2):253–265
Mochizuki T, Tauxe WN, Dobkin J, Shah AN, Shanker R, Todo S et al (1991) Detection of complications after liver transplantation by technetium-99 m mebrofenin hepatobiliary scintigraphy. Ann Nucl Med 5(3):103–107
Scott-Smith W, Raftery AT, Wraight EP, Calne RY (1983) Tc-99 m labeled HIDA imaging in suspected biliary leaks after liver transplantation. Clin Nucl Med 8(10):478–479
Gencoglu EA, Kocabas B, Moray G, Aktas A, Karakayali H, Haberal M (2008) Usefulness of hepatobiliary scintigraphy for the evaluation of living related liver transplant recipients in the early postoperative period. Transplant Proc 40(1):234–237
Al Sofayan MS, Ibrahim A, Helmy A, Al Saghier MI, Al Sebayel MI, Abozied MM (2009) Nuclear imaging of the liver: is there a diagnostic role of HIDA in posttransplantation? Transplant Proc 41(1):201–207
Lee JY, Hu W, Lee KH, Kwon CH, Lee EJ, Choi JY et al (2012) Differentiation of liver transplantation complications by quantitative analysis of dynamic hepatobiliary scintigraphy. Nucl Med Commun 33(3):255–261
Hopkins LO, Feyssa E, Parsikia A, Khanmoradi K, Zaki R, Campos S et al (2011) Tc-99m-Br IDA hepatobiliary (HIDA) scan has a low sensitivity for detecting biliary complications after orthotopic liver transplantation in patients with hyperbilirubinemia. Ann Nucl Med 25(10):762–767
Tsuji AB, Morita M, Li XK, Sogawa C, Sudo H, Sugyo A et al (2009) 18F-FDG PET for semiquantitative evaluation of acute allograft rejection and immunosuppressive therapy efficacy in rat models of liver transplantation. J Nucl Med 50(5):827–830
El-Serag HB (2011) Hepatocellular carcinoma. N Engl J Med 365(12):1118–1127
Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F et al (1996) Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334(11):693–699
Welker MW, Bechstein WO, Zeuzem S, Trojan J (2013) Recurrent hepatocellular carcinoma after liver transplantation—an emerging clinical challenge. Transpl Int 26(2):109–118
Torizuka T, Tamaki N, Inokuma T, Magata Y, Sasayama S, Yonekura Y et al (1995) In vivo assessment of glucose metabolism in hepatocellular carcinoma with FDG-PET. J Nucl Med 36(10):1811–1817
Seo S, Hatano E, Higashi T, Hara T, Tada M, Tamaki N et al (2007) Fluorine-18 fluorodeoxyglucose positron emission tomography predicts tumor differentiation, P-glycoprotein expression, and outcome after resection in hepatocellular carcinoma. Clin Cancer Res 13(2 Pt 1):427–433
Yang SH, Suh KS, Lee HW, Cho EH, Cho JY, Cho YB et al (2006) The role of (18)F-FDG-PET imaging for the selection of liver transplantation candidates among hepatocellular carcinoma patients. Liver Transpl 12(11):1655–1660
Kornberg A, Freesmeyer M, Barthel E, Jandt K, Katenkamp K, Steenbeck J et al (2009) 18F-FDG-uptake of hepatocellular carcinoma on PET predicts microvascular tumor invasion in liver transplant patients. Am J Transplant 9(3):592–600
Lee JW, Paeng JC, Kang KW, Kwon HW, Suh KS, Chung JK et al (2009) Prediction of tumor recurrence by 18F-FDG PET in liver transplantation for hepatocellular carcinoma. J Nucl Med 50(5):682–687
Kornberg A, Kupper B, Tannapfel A, Buchler P, Krause B, Witt U et al (2012) Patients with non-[18 F]fludeoxyglucose-avid advanced hepatocellular carcinoma on clinical staging may achieve long-term recurrence-free survival after liver transplantation. Liver Transpl 18(1):53–61
Lee SD, Kim SH, Kim YK, Kim C, Kim SK, Han SS et al (2013) (18)F-FDG-PET/CT predicts early tumor recurrence in living donor liver transplantation for hepatocellular carcinoma. Transpl Int 26(1):50–60
Detry O, Govaerts L, Deroover A, Vandermeulen M, Meurisse N, Malenga S et al (2015) Prognostic value of (18)F-FDG PET/CT in liver transplantation for hepatocarcinoma. World J Gastroenterol 21(10):3049–3054
Hong G, Suh KS, Suh SW, Yoo T, Kim H, Park MS et al (2016) Alpha-fetoprotein and (18)F-FDG positron emission tomography predict tumor recurrence better than Milan criteria in living donor liver transplantation. J Hepatol 64(4):852–859
Kim YI, Paeng JC, Cheon GJ, Suh KS, Lee DS, Chung JK et al (2016) Prediction of post-transplantation recurrence of hepatocellular carcinoma by using metabolic and volumetric indices of 18F-FDG PET/CT. J Nucl Med. doi:10.2967/jnumed.115.170076
Kobayashi T, Aikata H, Honda F, Nakano N, Nakamura Y, Hatooka M et al (2016) Preoperative fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography for prediction of microvascular invasion in small hepatocellular carcinoma. J Comput Assist Tomogr. doi:10.1097/RCT.0000000000000405
Kim YK, Lee KW, Cho SY, Han SS, Kim SH, Kim SK et al (2010) Usefulness 18F-FDG positron emission tomography/computed tomography for detecting recurrence of hepatocellular carcinoma in posttransplant patients. Liver Transpl 16(6):767–772
Darwish Murad S, Heimbach JK, Gores GJ, Rosen CB, Benson JT, Kim WR (2013) Excellent quality of life after liver transplantation for patients with perihilar cholangiocarcinoma who have undergone neoadjuvant chemoradiation. Liver Transpl 19(5):521–528
Kornberg A, Kupper B, Thrum K, Wilberg J, Sappler A, Gottschild D (2009) Recurrence-free long-term survival after liver transplantation in patients with 18F-FDG non-avid hilar cholangiocarcinoma on PET. Am J Transplant 9(11):2631–2636
Dholakia S, Mittal S, Quiroga I, Gilbert J, Sharples EJ, Ploeg RJ et al (2016) Pancreas transplantation: past, present, future. Am J Med. doi:10.1016/j.amjmed.2016.02.011
Toledo-Pereyra LH, Kristen KT, Mittal VK (1982) Scintigraphy of pancreatic transplants. AJR Am J Roentgenol 138(4):621–622
Hahn D, Bull U, Land W (1983) Pancreatic grafts. Nuclear perfusion imaging to detect vascular complications and rejection crises. Horm Metab Res Suppl. http://www.ncbi.nlm.nih.gov/pubmed/6345324(13):78-80
Shulkin BL, Dafoe DC, Wahl RL (1986) Simultaneous pancreatic-renal transplant scintigraphy. AJR Am J Roentgenol 147(6):1193–1196
George EA, Salimi Z, Carney K, Castaneda M, Garvin PJ (1988) Radionuclide surveillance of the allografted pancreas. AJR Am J Roentgenol 150(4):811–816
Patel B, Markivee CR, Mahanta B, Vas W, George E, Garvin P (1988) Pancreatic transplantation: scintigraphy, US, and CT. Radiology 167(3):685–687
Yuh WT, Wiese JA, Abu-Yousef MM, Rezai K, Sato Y, Berbaum KS et al (1988) Pancreatic transplant imaging. Radiology 167(3):679–683
Kuni CC, du Cret RP, Boudreau RJ (1989) Pancreas transplants: evaluation using perfusion scintigraphy. AJR Am J Roentgenol 153(1):57–61
Catafau AM, Lomena FJ, Ricart MJ, Pons F, Piera C, Pavia J et al (1989) Indium-111-labeled platelets in monitoring human pancreatic transplants. J Nucl Med 30(9):1470–1475
Hirsch H, Fernandez-Ulloa M, Munda R, Fisher RA, Moulton JS, Huth CJ (1991) Diagnosis of segmental necrosis in a pancreas transplant by thallium-201 perfusion scintigraphy. J Nucl Med 32(8):1605–1607
van der Hem LG, van der Linden CJ, Ticheler CH, Hoitsma AJ, Corstens FH (1994) Early detection of post-transplant pancreatic graft dysfunction with technetium-99m-HMPAO scintigraphy. J Nucl Med 35(9):1488–1490
Elgazzar AH, Munda R, Fernandez-Ulloa M, Clark J, Ryan JR, Hughes JA (1995) Scintigraphic evaluation of pancreatic transplants using technetium-99m-sestamibi. J Nucl Med 36(5):771–777
Vandermeer FQ, Manning MA, Frazier AA, Wong-You-Cheong JJ (2012) Imaging of whole-organ pancreas transplants. Radiographics. 32(2):411–435
Yates A, Parry C, Stephens M, Eynon A (1030) Imaging pancreas transplants. Br J Radiol 2013(86):20130428
Tolat PP, Foley WD, Johnson C, Hohenwalter MD, Quiroz FA (2015) Pancreas transplant imaging: how I do it. Radiology 275(1):14–27
Otsuki K, Kenmochi T, Saigo K, Maruyama M, Akutsu N, Iwashita C et al (2008) Evaluation of segmental pancreatic function using 11C-methionine positron emission tomography for safe operation of living donor pancreas transplantation. Transplant Proc 40(8):2562–2564
Otsuki K, Yoshikawa K, Kenmoshi T, Akutsu N, Maruyama M, Asano T et al (2014) Evaluation of insulin independence using 11C-methionine positron emission tomography after living-donor and brain-dead donor pancreas transplantation. Transplant Proc 46(6):1913–1916
Eriksson O, Eich T, Sundin A, Tibell A, Tufveson G, Andersson H et al (2009) Positron emission tomography in clinical islet transplantation. Am J Transpl 9(12):2816–2824
Freeby M, Goland R, Ichise M, Maffei A, Leibel R, Harris P (2008) VMAT2 quantitation by PET as a biomarker for beta-cell mass in health and disease. Diabetes Obes Metab 10(Suppl 4):98–108
Eriksson O, Jahan M, Johnstrom P, Korsgren O, Sundin A, Halldin C et al (2010) In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass. Nucl Med Biol 37(3):357–363
Fagerholm V, Mikkola KK, Ishizu T, Arponen E, Kauhanen S, Nagren K et al (2010) Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas. J Nucl Med 51(9):1439–1446
Kung MP, Hou C, Lieberman BP, Oya S, Ponde DE, Blankemeyer E et al (2008) In vivo imaging of beta-cell mass in rats using 18F-FP-(+)-DTBZ: a potential PET ligand for studying diabetes mellitus. J Nucl Med 49(7):1171–1176
Tornehave D, Kristensen P, Romer J, Knudsen LB, Heller RS (2008) Expression of the GLP-1 receptor in mouse, rat, and human pancreas. J Histochem Cytochem 56(9):841–851
Pattou F, Kerr-Conte J, Wild D (2010) GLP-1-receptor scanning for imaging of human beta cells transplanted in muscle. N Engl J Med 363(13):1289–1290
Christ E, Wild D, Forrer F, Brandle M, Sahli R, Clerici T et al (2009) Glucagon-like peptide-1 receptor imaging for localization of insulinomas. J Clin Endocrinol Metab 94(11):4398–4405
DePasquale EC, Schweiger M, Ross HJ (2014) A contemporary review of adult heart transplantation: 2012 to 2013. J Heart Lung Transplant 33(8):775–784
Lund LH, Edwards LB, Kucheryavaya AY, Dipchand AI, Benden C, Christie JD et al (2013) The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Official Adult Heart Transplant Report–2013; focus theme: age. J Heart Lung Transplant 32(10):951–964
Orrego CM, Cordero-Reyes AM, Estep JD, Loebe M, Torre-Amione G (2012) Usefulness of routine surveillance endomyocardial biopsy 6 months after heart transplantation. J Heart Lung Transplant 31(8):845–849
Miller CA, Fildes JE, Ray SG, Doran H, Yonan N, Williams SG et al (2013) Non-invasive approaches for the diagnosis of acute cardiac allograft rejection. Heart 99(7):445–453
Lee KJ, Wallis JW, Miller TR, Bolman RM 3rd (1990) The clinical utility of radionuclide ventriculography in cardiac transplantation. J Nucl Med 31(12):1933–1939
Flotats A, Carrio I (2006) Value of radionuclide studies in cardiac transplantation. Ann Nucl Med 20(1):13–21
Narula J, Southern JF, Dec GW, Palacios IF, Newell JB, Fallon JT et al (1995) Antimyosin uptake and myofibrillar lysis in dilated cardiomyopathy. J Nucl Cardiol 2(6):470–477
Hesse B, Mortensen SA, Folke M, Brodersen AK, Aldershvile J, Pettersson G (1995) Ability of antimyosin scintigraphy monitoring to exclude acute rejection during the first year after heart transplantation. J Heart Lung Transpl 14(1 Pt 1):23–31
Schutz A, Breuer M, Kemkes BM (1997) Antimyosin antibodies in cardiac rejection. Ann Thorac Surg 63(2):578–581
Ballester M, Obrador D, Carrio I, Auge JM, Moya C, Pons-Llado G et al (1990) Indium-111-monoclonal antimyosin antibody studies after the first year of heart transplantation. Identification of risk groups for developing rejection during long-term follow-up and clinical implications. Circulation 82(6):2100–2107
Rubin PJ, Hartman JJ, Hasapes JP, Bakke JE, Bergmann SR (1996) Detection of cardiac transplant rejection with 111In-labeled lymphocytes and gamma scintigraphy. Circulation 94(9 Suppl):II298–II303
Kown MH, Strauss HW, Blankenberg FG, Berry GJ, Stafford-Cecil S, Tait JF et al (2001) In vivo imaging of acute cardiac rejection in human patients using (99m)technetium labeled annexin V. Am J Transpl 1(3):270–277
Rodney RA, Johnson LL, Blood DK, Barr ML (1994) Myocardial perfusion scintigraphy in heart transplant recipients with and without allograft atherosclerosis: a comparison of thallium-201 and technetium 99m sestamibi. J Heart Lung Transpl 13(2):173–180
Lamich R, Ballester M, Marti V, Brossa V, Aymat R, Carrio I et al (1998) Efficacy of augmented immunosuppressive therapy for early vasculopathy in heart transplantation. J Am Coll Cardiol 32(2):413–419
Carlsen J, Toft JC, Mortensen SA, Arendrup H, Aldershvile J, Hesse B (2000) Myocardial perfusion scintigraphy as a screening method for significant coronary artery stenosis in cardiac transplant recipients. J Heart Lung Transpl 19(9):873–878
Elhendy A, Sozzi FB, van Domburg RT, Vantrimpont P, Valkema R, Krenning EP et al (2000) Accuracy of dobutamine tetrofosmin myocardial perfusion imaging for the noninvasive diagnosis of transplant coronary artery stenosis. J Heart Lung Transpl 19(4):360–366
Ciliberto GR, Ruffini L, Mangiavacchi M, Parolini M, Sara R, Massa D et al (2001) Resting echocardiography and quantitative dipyridamole technetium-99m sestamibi tomography in the identification of cardiac allograft vasculopathy and the prediction of long-term prognosis after heart transplantation. Eur Heart J 22(11):964–971
Elhendy A, van Domburg RT, Vantrimpont P, Poldermans D, Bax JJ, van Gelder T et al (2002) Prediction of mortality in heart transplant recipients by stress technetium-99m tetrofosmin myocardial perfusion imaging. Am J Cardiol 89(8):964–968
Wu YW, Yen RF, Lee CM, Ho YL, Chou NK, Wang SS et al (2005) Diagnostic and prognostic value of dobutamine thallium-201 single-photon emission computed tomography after heart transplantation. J Heart Lung Transpl 24(5):544–550
Hacker M, Tausig A, Romuller B, Hoyer X, Klauss V, Stempfle U et al (2005) Dobutamine myocardial scintigraphy for the prediction of cardiac events after heart transplantation. Nucl Med Commun 26(7):607–612
Manrique A, Bernard M, Hitzel A, Bubenheim M, Tron C, Agostini D et al (2010) Diagnostic and prognostic value of myocardial perfusion gated SPECT in orthotopic heart transplant recipients. J Nucl Cardiol 17(2):197–206
Wenning C, Stypmann J, Papavassilis P, Sindermann J, Schober O, Hoffmeier A et al (2012) Left ventricular dilation and functional impairment assessed by gated SPECT are indicators of cardiac allograft vasculopathy in heart transplant recipients. J Heart Lung Transpl 31(7):719–728
Wenning C, Vrachimis A, Dell Aquila A, Penning A, Stypmann J, Schafers M (2015) Inhomogeneous myocardial stress perfusion in SPECT studies predicts future allograft dysfunction in heart transplant recipients. EJNMMI Res 5(1):51
Wu YW, Chen YH, Wang SS, Jui HY, Yen RF, Tzen KY et al (2010) PET assessment of myocardial perfusion reserve inversely correlates with intravascular ultrasound findings in angiographically normal cardiac transplant recipients. J Nucl Med 51(6):906–912
Allen-Auerbach M, Schoder H, Johnson J, Kofoed K, Einhorn K, Phelps ME et al (1999) Relationship between coronary function by positron emission tomography and temporal changes in morphology by intravascular ultrasound (IVUS) in transplant recipients. J Heart Lung Transpl 18(3):211–219
Guertner C, Krause BJ, Klepzig H Jr, Herrmann G, Lelbach S, Vockert EK et al (1995) Sympathetic re-innervation after heart transplantation: dual-isotope neurotransmitter scintigraphy, norepinephrine content and histological examination. Eur J Nucl Med 22(5):443–452
De Marco T, Dae M, Yuen-Green MS, Kumar S, Sudhir K, Keith F et al (1995) Iodine-123 metaiodobenzylguanidine scintigraphic assessment of the transplanted human heart: evidence for late reinnervation. J Am Coll Cardiol 25(4):927–931
Estorch M, Camprecios M, Flotats A, Mari C, Berna L, Catafau AM et al (1999) Sympathetic reinnervation of cardiac allografts evaluated by 123I-MIBG imaging. J Nucl Med 40(6):911–916
Bengel FM, Ueberfuhr P, Ziegler SI, Nekolla S, Reichart B, Schwaiger M (1999) Serial assessment of sympathetic reinnervation after orthotopic heart transplantation. A longitudinal study using PET and C-11 hydroxyephedrine. Circulation 99(14):1866–1871
Balsam LB, Robbins RC (2007) Current trends in heart transplantation. Scand J Surg 96(2):125–130
Ergul N, Cermik TF (2011) FDG-PET or PET/CT in fever of unknown origin: the diagnostic role of underlying primary disease. Int J Mol Imaging 2011:318051
Graute V, Jansen N, Sohn HY, Becker A, Klein B, Schmid I et al (2012) Diagnostic role of whole-body [18F]-FDG positron emission tomography in patients with symptoms suspicious for malignancy after heart transplantation. J Heart Lung Transpl 31(9):958–966
Delgado JF, Alonso-Pulpon L, Mirabet S, Almenar L, Villa FP, Gonzalez-Vilchez F et al (2016) Cancer incidence in heart transplant recipients with previous neoplasia history. Am J Transpl 16(5):1569–1578
Stanchina ML, Tantisira KG, Aquino SL, Wain JC, Ginns LC (2002) Association of lung perfusion disparity and mortality in patients with cystic fibrosis awaiting lung transplantation. J Heart Lung Transpl 21(2):217–225
Fox BD, Nachum IB, Bernstine H, Amital A, Bakal I, Peled N et al (2008) Graft side-mismatching for single-lung transplantation does not affect outcomes: role of the pre-operative quantitative lung perfusion scan. J Heart Lung Transpl 27(3):272–275
Sokai A, Handa T, Chen F, Tanizawa K, Aoyama A, Kubo T et al (2016) Serial perfusion in native lungs in patients with idiopathic pulmonary fibrosis and other interstitial lung diseases after single lung transplantation. Clin Transpl 30(4):407–414
Kramer MR, Marshall SE, McDougall IR, Kloneck A, Starnes VA, Lewiston NJ et al (1991) The distribution of ventilation and perfusion after single-lung transplantation in patients with pulmonary fibrosis and pulmonary hypertension. Transpl Proc 23(1 Pt 2):1215–1216
Colt HG, Cammilleri S, Khelifa F, Dumon JF, Garbe L, Noirclerc M et al (1994) Comparison of SPECT lung perfusion with transbronchial lung biopsy after lung transplantation. Am J Respir Crit Care Med 150(2):515–520
Christie JD, Sager JS, Kimmel SE, Ahya VN, Gaughan C, Blumenthal NP et al (2005) Impact of primary graft failure on outcomes following lung transplantation. Chest 127(1):161–165
Belmaati EO, Iversen M, Kofoed KF, Nielsen MB, Mortensen J (2012) Scintigraphy at 3 months after single lung transplantation and observations of primary graft dysfunction and lung function. Interact CardioVasc Thorac Surg 14(6):792–796
Humplik BI, Sandrock D, Aurisch R, Richter WS, Ewert R, Munz DL (2005) Scintigraphic results in patients with lung transplants: a prospective comparative study. Nuklearmedizin 44(2):62–68
Andrade M, Krug B, Abraham C, Pirson AS, Delaunois L, Vander Borght T (2008) Unusual ventilation-perfusion scans in the follow-up of two lung transplant patients. Clin Nucl Med 33(10):713–716
Karetzky MS, Jasani RR, Zubair MA (1996) Thallium-201 scintigraphy in the evaluation of graft dysfunction in lung transplantation. Newark Beth Israel Medical Center Lung Transplant Group. Eur Respir J 9(12):2553–2559
Hardoff R, Steinmetz AP, Krausz Y, Bar-Sever Z, Liani M, Kramer MR (2000) The prognostic value of perfusion lung scintigraphy in patients who underwent single-lung transplantation for emphysema and pulmonary fibrosis. J Nucl Med 41(11):1771–1776
Ouwens JP, van der Bij W, van der Mark TW, Geertsma A, Piers DA, de Boer WJ et al (2004) The value of ventilation scintigraphy after single lung transplantation. J Heart Lung Transpl 23(1):115–121
Johansson A, Moonen M, Enocson A, Martensson G, Bake B (2005) Detection of chronic rejection by quantitative ventilation scintigrams in lung-transplanted patients: a pilot study. Clin Physiol Funct Imaging 25(3):183–187
Shinya T, Sato S, Kato K, Gobara H, Akaki S, Date H et al (2008) Assessment of mean transit time in the engrafted lung with 133Xe lung ventilation scintigraphy improves diagnosis of bronchiolitis obliterans syndrome in living-donor lobar lung transplant recipients. Ann Nucl Med 22(1):31–39
Ross DJ, Waters PF, Waxman AD, Koerner SK, Mohsenifar Z (1993) Regional distribution of lung perfusion and ventilation at rest and during steady-state exercise after unilateral lung transplantation. Chest 104(1):130–135
Starobin D, Shitrit D, Steinmetz A, Fink G, Hardoff R, Kramer MR (2007) Quantitative lung perfusion following single lung transplantation. Thorac Cardiovasc Surg 55(1):48–52
Bergstedt HF, Korlof B, Lind MG, Wersall J (1978) Scintigraphy of human autologous rib transplants to a partially resected mandible. Scand J Plast Reconstr Surg 12(2):151–156
Frame JW, Edmondson HD, O’Kane MM (1983) A radio-isotope study of the healing of mandibular bone grafts in patients. Br J Oral Surg 21(4):277–289
Zinberg EM, Wood MB, Brown ML (1985) Vascularized bone transfer: evaluation of viability by postoperative bone scan. J Reconstr Microsurg 2(1):13–19
Karcher H, Fuger G, Borbely L (1988) Bone scintigraphy of vascularized bone transfer in maxillofacial surgery. Oral Surg Oral Med Oral Pathol 65(5):519–522
Takato T, Harii K, Nakatsuka T (1988) The sequential evaluation of bone scintigraphy: an analysis of revascularised bone grafts. Br J Plast Surg 41(3):262–269
Berding G, Bothe K, Gratz KF, Schmelzeisen R, Neukam FW, Hundeshagen H (1994) Bone scintigraphy in the evaluation of bone grafts used for mandibular reconstruction. Eur J Nucl Med 21(2):113–117
Harada H, Takinami S, Makino S, Kitada H, Yamashita T, Notani K et al (2000) Three-phase bone scintigraphy and viability of vascularized bone grafts for mandibular reconstruction. Int J Oral Maxillofac Surg 29(4):280–284
Buyukdereli G, Guney IB, Ozerdem G, Kesiktas E (2006) Evaluation of vascularized graft reconstruction of the mandible with Tc-99m MDP bone scintigraphy. Ann Nucl Med 20(2):89–93
Schuepbach J, Dassonville O, Poissonnet G, Demard F (2007) Early postoperative bone scintigraphy in the evaluation of microvascular bone grafts in head and neck reconstruction. Head Face Med 3:20
Hervas I, Floria LM, Bello P, Baquero MC, Perez R, Barea J et al (2001) Microvascularized fibular graft for mandibular reconstruction: detection of viability by bone scintigraphy and SPECT. Clin Nucl Med 26(3):225–229
Schimming R, Juengling FD, Lauer G, Schmelzeisen R (2000) Evaluation of microvascular bone graft reconstruction of the head and neck with 3-D 99mTc-DPD SPECT scans. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90(6):679–685
Aydogan F, Akbay E, Cevik C, Kalender E (2014) Blood-pool SPECT in addition to bone SPECT in the viability assessment in mandibular reconstruction. Eur Rev Med Pharmacol Sci 18(4):587–592
Lauer I, Czech N, Zieron J, Sieg P, Richter E, Baehre M (2000) Assessment of the viability of microvascularized bone grafts after mandibular reconstruction by means of bone SPET and semiquantitative analysis. Eur J Nucl Med 27(10):1552–1556
Ramsay SC, Yeates MG, Ho LC (1991) Bone scanning in the early assessment of nasal bone graft viability. J Nucl Med 32(1):33–36
Kirschner MH, Manthey N, Tatsch K, Nerlich A, Hahn K, Hofmann GO (1999) Use of three-phase bone scans and SPET in the follow-up of patients with allogenic vascularized femur transplants. Nucl Med Commun 20(6):517–524
Manthey N, Kirschner MH, Nerlich A, Hofmann GO, Tatsch K, Hahn K (2001) 3-phase bone imaging and SPECT in the follow up of patients with allogenic vascularized knee joint transplants. Nuklearmedizin 40(6):187–192
Droll KP, Prasad V, Ciorau A, Gray BG, McKee MD (2007) The use of postoperative bone scintigraphy to predict graft retention. Can J Surg 50(4):261–265
Malizos KN, Soucacos PN, Vragalas V, Dailiana ZH, Schina I, Fotopoulos A (1995) Three phase bone scanning and digital arteriograms for monitoring vascularized fibular grafts in femoral head necrosis. Int Angiol 14(3):319–326
Jadvar H, Desai B, Conti PS (2015) Sodium 18F-fluoride PET/CT of bone, joint, and other disorders. Semin Nucl Med 45(1):58–65
Schliephake H, Berding G, Knapp WH, Sewilam S (1999) Monitoring of graft perfusion and osteoblast activity in revascularised fibula segments using [18F]-positron emission tomography. Int J Oral Maxillofac Surg 28(5):349–355
Berding G, Schliephake H, van den Hoff J, Knapp WH (2001) Assessment of the incorporation of revascularized fibula grafts used for mandibular reconstruction with F-18-PET. Nuklearmedizin 40(2):51–58
Quon A, Dodd R, Iagaru A, de Abreu MR, Hennemann S, Alves Neto JM et al (2012) Initial investigation of (1)(8)F-NaF PET/CT for identification of vertebral sites amenable to surgical revision after spinal fusion surgery. Eur J Nucl Med Mol Imaging 39(11):1737–1744
Brans B, Weijers R, Halders S, Wierts R, Peters M, Punt I et al (2012) Assessment of bone graft incorporation by 18 F-fluoride positron-emission tomography/computed tomography in patients with persisting symptoms after posterior lumbar interbody fusion. EJNMMI Res 2(1):42
Piert M, Winter E, Becker GA, Bilger K, Machulla H, Muller-Schauenburg W et al (1999) Allogenic bone graft viability after hip revision arthroplasty assessed by dynamic [18F]fluoride ion positron emission tomography. Eur J Nucl Med 26(6):615–624
Brenner W, Vernon C, Conrad EU, Eary JF (2004) Assessment of the metabolic activity of bone grafts with (18)F-fluoride PET. Eur J Nucl Med Mol Imaging 31(9):1291–1298
Bernstein P, Beuthien-Baumann B, Kotzerke J, Hofheinz F, Zessin J, Stiehler M et al (2014) Periacetabular bone metabolism following hip revision surgery. PET-based evaluation of allograft osteointegration. Nuklearmedizin. 53(4):147–154
Sorensen J, Ullmark G, Langstrom B, Nilsson O (2003) Rapid bone and blood flow formation in impacted morselized allografts: positron emission tomography (PET) studies on allografts in 5 femoral component revisions of total hip arthroplasty. Acta Orthop Scand 74(6):633–643
Temmerman OP, Raijmakers PG, Heyligers IC, Comans EF, Lubberink M, Teule GJ et al (2008) Bone metabolism after total hip revision surgery with impacted grafting: evaluation using H2 15O and [18F]fluoride PET; a pilot study. Mol Imaging Biol 10(5):288–293
Itala A, Alihanka S, Kosola J, Kemppainen J, Ranne J, Kajander S (2016) Tendon graft healing in multiligament reconstructed knee detected by FDG-PET/CT: a pilot study. Scand J Surg 105(2):133–138
Murube-del-Castillo J (1986) Transplantation of salivary gland to the lacrimal basin. Scand J Rheumatol Suppl 61:264–267
Lauer I, Sieg P, Bahre M, Richter E (1998) Salivary gland scintigraphy using technetium-99m-pertechnetate after autotransplantation of the submandibular salivary gland in the correction of dry eye. Eur J Nucl Med 25(2):128–131
Zhang L, Zhu ZH, Dai HJ, Cai ZG, Mao C, Peng X et al (2007) Application of 99mTc-pertechnetate scintigraphy to microvascular autologous transplantation of the submandibular gland in patients with severe keratoconjunctivitis sicca. J Nucl Med 48(9):1431–1435
Wu F, Weng S, Li C, Sun J, Li L, Gao Q (2015) Submandibular gland transfer for the prevention of postradiation xerostomia in patients with head and neck cancer: a systematic review and meta-analysis. ORL J Otorhinolaryngol Relat Spec 77(2):70–86
Jha N, Seikaly H, McGaw T, Coulter L (2000) Submandibular salivary gland transfer prevents radiation-induced xerostomia. Int J Radiat Oncol Biol Phys 46(1):7–11
Liu XK, Su Y, Jha N, Hong MH, Mai HQ, Fan W et al (2011) Submandibular salivary gland transfer for the prevention of radiation-induced xerostomia in patients with nasopharyngeal carcinoma: 5-Year outcomes. Head Neck 33(3):389–395
Zhang X, Liu F, Lan X, Yu L, Wu W, Wu X et al (2014) Clinical observation of submandibular gland transfer for the prevention of xerostomia after radiotherapy for nasopharyngeal carcinoma: a prospective randomized controlled study of 32 cases. Radiat Oncol 9:62
Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES (2011) The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood 117(19):5019–5032
Bakker NA, van Imhoff GW, Verschuuren EA, van Son WJ (2007) Presentation and early detection of post-transplant lymphoproliferative disorder after solid organ transplantation. Transpl Int 20(3):207–218
Borhani AA, Hosseinzadeh K, Almusa O, Furlan A, Nalesnik M. Imaging of posttransplantation lymphoproliferative disorder after solid organ transplantation. Radiographics. 2009;29(4):981-1000; discussion -2
Barrington SF, Mikhaeel NG, Kostakoglu L, Meignan M, Hutchings M, Mueller SP et al (2014) Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol 32(27):3048–3058
Marom EM, McAdams HP, Butnor KJ, Coleman RE (2004) Positron emission tomography with fluoro-2-deoxy-d-glucose (FDG-PET) in the staging of post transplant lymphoproliferative disorder in lung transplant recipients. J Thorac Imaging 19(2):74–78
O’Conner AR, Franc BL (2005) FDG PET imaging in the evaluation of post-transplant lymphoproliferative disorder following renal transplantation. Nucl Med Commun 26(12):1107–1111
McCormack L, Hany TI, Hubner M, Petrowsky H, Mullhaupt B, Knuth A et al (2006) How useful is PET/CT imaging in the management of post-transplant lymphoproliferative disease after liver transplantation? Am J Transpl 6(7):1731–1736
Bakker NA, Pruim J, de Graaf W, van Son WJ, van der Jagt EJ, van Imhoff GW (2006) PTLD visualization by FDG-PET: improved detection of extranodal localizations. Am J Transpl 6(8):1984–1985
Bianchi E, Pascual M, Nicod M, Delaloye AB, Duchosal MA (2008) Clinical usefulness of FDG-PET/CT scan imaging in the management of posttransplant lymphoproliferative disease. Transplantation 85(5):707–712
von Falck C, Maecker B, Schirg E, Boerner AR, Knapp WH, Klein C et al (2007) Post transplant lymphoproliferative disease in pediatric solid organ transplant patients: a possible role for [18F]-FDG-PET(/CT) in initial staging and therapy monitoring. Eur J Radiol 63(3):427–435
Dierickx D, Tousseyn T, Requile A, Verscuren R, Sagaert X, Morscio J et al (2013) The accuracy of positron emission tomography in the detection of posttransplant lymphoproliferative disorder. Haematologica 98(5):771–775
Panagiotidis E, Quigley AM, Pencharz D, Ardeshna K, Syed R, Sajjan R et al (2014) (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in diagnosis of post-transplant lymphoproliferative disorder. Leuk Lymphoma 55(3):515–519
Takehana CS, Twist CJ, Mosci C, Quon A, Mittra E, Iagaru A (2014) (18)F-FDG PET/CT in the management of patients with post-transplant lymphoproliferative disorder. Nucl Med Commun 35(3):276–281
Network. NCC. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) (2016) Non-Hodgkin’s Lymphomas Version 3.2016. https://www.nccn.org/professionals/physician_gls/pdf/nhl.pdf