Article (Scientific journals)
Guérir l'infection par le VIH: Un objectif réaliste?
DARCIS, Gilles; Moutschen, Michel
2017In Revue Médicale de Liège, 72 (9), p. 388-392
Peer reviewed
 

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Keywords :
Cure; HIV; Latent reservoirs; Human immunodeficiency virus
Abstract :
[en] More than 30 years after its discovery, human immunodeficiency virus (HIV) continues to be a major global public health issue. Antiretroviral therapy increases survival and quality of life of HIV-infected patients but is not curative. Indeed, interruption of therapy invariably leads to the re-emergence of detectable viral replication, since HIV persists in extremely long-lived viral latent reservoirs. Those viral latent reservoirs constitute the major source of viral recovery following antiretroviral treatment interruption and are considered as the most important hurdle to HIV eradication. Multiple strategies aimed at targeting the HIV latent reservoirs are intensively being explored. We discuss here the most recent innovative works that will hopefully contribute to find a cure for HIV.
Disciplines :
Immunology & infectious disease
Author, co-author :
DARCIS, Gilles ;  Centre Hospitalier Universitaire de Liège - CHU > Service des maladies infectieuses - médecine interne
Moutschen, Michel  ;  Université de Liège - ULiège > Département des sciences cliniques > GIGA-R:Immunopath. - Maladies infect. et médec. inter. gén.
Language :
French
Title :
Guérir l'infection par le VIH: Un objectif réaliste?
Alternative titles :
[en] HIV cure: A realistic perspective?
Publication date :
2017
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Revue Medicale de Liege
Volume :
72
Issue :
9
Pages :
388-392
Peer reviewed :
Peer reviewed
Available on ORBi :
since 17 January 2018

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