Thoraco-abdominal normothermic regional perfusion (TA-NRP); donation after circulatory death (DCD); heart donation; heart transplantation; transoesophageal echocardiography (TOE); Echocardiography, Transesophageal; Humans; Perfusion/methods; Tissue Donors; Heart Transplantation/methods; Tissue and Organ Procurement; Perfusion; Transplantation
Abstract :
[en] Heart donation after circulatory death (DCD) can significantly expand the heart donor pool, helping to overcome the problem of organ shortage and the increase in waiting list mortality and morbidity. To improve the outcome of DCD heart transplantation, thoraco-abdominal normothermic regional perfusion (TA-NRP) can be performed by selectively restoring circulation followed by in vivo functional heart assessment. Here, we report on the use of periprocedural transoesophageal echocardiography (TOE) as a minimally invasive cardiac assessment tool during different stages of a DCD heart procurement procedure using TA-NRP. We conclude that TOE is a valuable method to assess the donor heart for transplantation eligibility before and after withdrawal of life-sustaining therapy and during subsequent TA-NRP.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Vandenbriele, Christophe ; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
Brouckaert, Janne ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium ; Department of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium
Hans, Grégory ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation
Tchana-Sato, Vincent ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique
Vandendriessche, Katrien ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium ; Department of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium
Gunst, Jan ; Clinical Department and Laboratory of Intensive Care Medicine, KU Leuven, Leuven, Belgium
Ancion, Arnaud ; Centre Hospitalier Universitaire de Liège - CHU > > Service de cardiologie
Van Cleemput, Johan ; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
Ledoux, Didier ; Centre Hospitalier Universitaire de Liège - CHU > > Service des soins intensifs
Rex, Steffen ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium ; Department of Anesthesiology, University Hospitals Leuven, Leuven, Belgium
Neyrinck, Arne ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium ; Department of Anesthesiology, University Hospitals Leuven, Leuven, Belgium
Rega, Filip ; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium ; Department of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium
Language :
English
Title :
The role of transesophageal echocardiography in guiding heart donation after circulatory death.
We sincerely thank the collaborators of the Leuven and Liège DCD transplantation program and the staff of the intensive care units. JG received a postdoctoral research fellowship granted by the University Hospitals Leuven. CV received a clinical research grant of the “Klinische Onderzoeksraad” (KOOR, UZ Leuven). JB received a grant of the Foundation for Cardiac Surgery.We sincerely thank the collaborators of the Leuven and Liège DCD transplantation program and the staff of the intensive care units. JG received a postdoctoral research fellowship granted by the University Hospitals Leuven. CV received a clinical research grant of the “Klinische Onderzoeksraad” (KOOR, UZ Leuven). JB received a grant of the Foundation for Cardiac Surgery.
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