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Antigens of the basement membrane and the peritumoral stroma in human colonic adenocarcinomas: an immunofluorescence study.
Burtin, P.; Chavanel, G.; Foidart, Jean-Michel et al.
1982In International Journal of Cancer, 30 (1), p. 13-20
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Abstract :
[en] Twenty colonic adenocarcinomas were studied by immunofluorescence with antisera against components of the basement membrane: type IV collagen, laminin and heparan sulfate-rich proteoglycan, as well as antisera against antigens of the connective tissue: type-III collagen, fibronectin and hyaluronectin. Marked alterations of the basement membranes were consistently observed on staining with each one of the first three antisera. In contrast, staining of the normal components of connective tissue was in most cases as intense as in normal colonic mucosa. Hyaluronectin, a marker of peritumoral stroma, was found to be present in 12 out 15 tumors studied.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Burtin, P.
Chavanel, G.
Foidart, Jean-Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique - Labo de biologie des tumeurs et du développement
Martin, E.
Language :
English
Title :
Antigens of the basement membrane and the peritumoral stroma in human colonic adenocarcinomas: an immunofluorescence study.
Publication date :
1982
Journal title :
International Journal of Cancer
ISSN :
0020-7136
eISSN :
1097-0215
Publisher :
Wiley Liss, Inc., New York, United States - New York
Volume :
30
Issue :
1
Pages :
13-20
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 11 February 2011

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