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Yeast two-hybrid 法による複製開始蛋白質 orgin recognition complex の構造・機能解析
http://hdl.handle.net/2298/9408
http://hdl.handle.net/2298/94088860351e-d87e-414c-85a9-bc672f328620
名前 / ファイル | ライセンス | アクション |
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23-0169.pdf (895.6 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2014-12-11 | |||||
タイトル | ||||||
タイトル | Yeast two-hybrid 法による複製開始蛋白質 orgin recognition complex の構造・機能解析 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題 | ORC, Orc2p | |||||
資源タイプ | ||||||
資源タイプ | thesis | |||||
著者 |
松田, 和也
× 松田, 和也 |
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別言語の著者 |
松田, 和也
× 松田, 和也 |
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内容記述 | ||||||
内容記述 | The initiation of chromosomal DNA replication must be tightly regulated, and coordinated with cell division, to replicate the genome just once per cell cycle. To understand this regulation, it is important to study the structure and function of the initiator of chromosomal DNA replication. Origin recognition complex (ORC), a sixprotein complex (Orc1p to Orc6p), is the most likely initiator of chromosomal DNA replication in eukaryotes. Although ORC of Saccharomyces cerevisiae has been studied extensively from biochemical and genetic perspectives, its structure remains unknown. Previous studies suggested that ORC has functions other than DNA replication, such as gene silencing, but the molecular mechanisms of these functions remain unknown. In this study, I used yeast two-hybrid analysis to search for ORC-binding proteins and to examine interaction between ORC subunits. |
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書誌情報 | 発行年 2008-03-25 | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
形態 | ||||||
895632 bytes | ||||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
日本十進分類法 | ||||||
主題 | 377.5 | |||||
その他の言語のタイトル | ||||||
その他のタイトル | Structural and functional analyses of origin recognition complex using yeast two-hybrid system | |||||
タイトル(ヨミ) | ||||||
その他のタイトル | Yeast two-hybrid ホウ ニヨル フクセイ カイシ タンパクシツ origin recognition complex ノ コウゾウ キノウ カイセキ | |||||
出版者 | ||||||
出版者 | 熊本大学 | |||||
資源タイプ | ||||||
内容記述 | 学位論文(Thesis) | |||||
資源タイプ・ローカル | ||||||
博士論文 | ||||||
資源タイプ・NII | ||||||
Thesis or Dissertation | ||||||
資源タイプ・DCMI | ||||||
text | ||||||
資源タイプ・ローカル表示コード | ||||||
03 | ||||||
学位番号 | ||||||
甲博薬第169号 |