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Growth-accelerating effects of alkaline extracts from the pituitary glands of the spring salmon (Oncorhynchus tschawytscha)

University of British Columbia

An alkaline extract from the anterior lobe of the beef pituitary proved a potent source of a growth hormone with injections to rats. Injections of this extract to goldfish resulted in an 18% weight increase within eight days, which appears significant when compared to their controls. A similar method of preparation was used for an extract of the pituitary gland of the Pacific Salmon, Onoorhynohus tschawytscha. Injections of this extract failed to accelerate the growth of test rats. Injections to goldfish resulted in a confusing pattern with both increases and decreases in weight being observed, however, the results indicate the presence of a growth-accelerating hormone. Substantiation of this growth-accelerating effect of alkaline extracts of the fish pituitary is necessary in view of the conflicting results obtained.

Text

2012-03-09

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http://hdl.handle.net/2429/41291

Zoology

University of British Columbia

Graduate