Guidelines for lupus anticoagulant testing in South Africa
Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
The Society of Medical Laboratory Technologists of South Africa
Abstract
ENGLISH ABSTRACT: The lupus anticoagulant (LA) refers to the prolongation of certain coagulation tests due to the action of heterogenous autoantibodies.
However, the LA is a misnomer since it is associated with thrombosis in vivo, and most commonly is detected as an incidental, transient
laboratory finding associated with conditions such as autoimmune diseases, infections and even in healthy individuals. Repeatedly
positive LA testing in the setting of thrombotic and/or obstetric complications is required to diagnose the antiphospholipid syndrome
(APS). This review intends to provide clarity on LA testing in the South African context and to provide a national guideline in order to
standardise LA testing, interpretation and reporting of results.
Description
CITATION: Bailly, J., et al. 2020. Guidelines for lupus anticoagulant testing in South Africa. Journal of Medical Laboratory Science and Technology of South Africa, 2(1):6-12, doi:The Journal of Medical Laboratory Science & Technology South Africa 2020; 2(1):6-12, doi:10.36303/JMLSTSA.2020.2.1.39.
The original publication is available at https://jmlstsa.smltsa.org.za
The original publication is available at https://jmlstsa.smltsa.org.za
Keywords
Lupus -- Medical tests (Diagnosis), Anticoagulants (Medicine), Antiphospholipid syndrome, Diagnosis, Laboratory
Citation
Bailly, J., et al. 2020. Guidelines for lupus anticoagulant testing in South Africa. Journal of Medical Laboratory Science and Technology of South Africa, 2(1):6-12, doi:The Journal of Medical Laboratory Science & Technology South Africa 2020; 2(1):6-12, doi:10.36303/JMLSTSA.2020.2.1.39