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Título: | Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572 |
Autor: | Diez-Echave, Patricia; Martín-Cabrejas, Izaskun; Garrido-Mesa, José; Langa, Susana; Vezza, Teresa; Landete, José María CSIC ORCID; Hidalgo-García, Laura; Algieri, Francesca; Mayer, Melinda J.; Narbad, Arjan; García Lafuente, Ana María; Medina, Margarita; Rodríguez-Nogales, Alba; Rodríguez-Cabezas, María Elena; Gálvez, Julio; Arques Orobón, Juan Luis | Palabras clave: | DSS-induced colitic model Limosilactobacillus reuteri Colonic model Immunomodulation Probiotic Protective effect Reuterin |
Fecha de publicación: | 29-may-2021 | Editor: | Multidisciplinary Digital Publishing Institute | Citación: | Nutrients 13(6): 1860 (2021) | Resumen: | Limosilactobacillus reuteri INIA P572 is a strain able to produce the antimicrobial compound reuterin in dairy products, exhibiting a protective effect against some food-borne pathogens. In this study, we investigated some probiotic properties of this strain such as resistance to gastrointestinal passage or to colonic conditions, reuterin production in a colonic environment, and immunomodulatory activity, using different in vitro and in vivo models. The results showed a high resistance of this strain to gastrointestinal conditions, as well as capacity to grow and produce reuterin in a human colonic model. Although the in vitro assays using the RAW 264.7 macrophage cell line did not demonstrate direct immunomodulatory properties, the in vivo assays using a Dextran Sulphate Sodium (DSS)-induced colitic mice model showed clear immunomodulatory and protective effects of this strain. | Descripción: | 18 Pág. Departamento de Tecnología de Alimentos | Versión del editor: | https://doi.org/10.3390/nu13061860 | URI: | http://hdl.handle.net/10261/286737 | DOI: | 10.3390/nu13061860 | ISSN: | 2072-6643 |
Aparece en las colecciones: | (INIA) Artículos |
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Probiotic-and-functional-properties-of-limosilactobacillus .pdf | artículo | 2,88 MB | Adobe PDF | Visualizar/Abrir |
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