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Título: | The politics of biomedical platforms: controversy around the molecularization of cytogenetics in prenatal diagnosis |
Autor: | Turrini, Mauro CSIC ORCID | Palabras clave: | Biomedical platform Molecularization Prenatal diagnosis Chromosomal microarray Cytogenetics Controversies |
Fecha de publicación: | 2016 | Editor: | Taylor & Francis | Citación: | New Genetics and Society 36(2): 97-117 (2016) | Resumen: | The introduction of a new technique based on molecular cytogenetics (the comparative genomic hybridization microarray, Chromosomal Micro-Array) in prenatal diagnosis is here used as an occasion to politically elaborate Cambrosio’s and Keating’s framework of “biomedical platform.” The uncertainty generated by molecularization leaves the field open for two different modalities of implementation: using targeted microarrays to completely replace traditional karyotyping versus using genome-wide analysis of chromosomal anomalies only in at-risk pregnancies. Retracing the global scientific controversy on this issue and, particularly, the heated debate that has taken place in Italy, the paper intends to analyze the rise of a biomedical platform in prenatal diagnosis as a multi-layered phenomenon. Diverging epistemological strategies to deal with uncertainty, professional interests, relationship between medical practice, innovation and research, and patient subjectivities interact with each other, by shedding light on the inherent political dimension in the epistemological and material of an emerging biomedical platform. | Versión del editor: | https://doi.org/10.1080/14636778.2017.1302324 | URI: | http://hdl.handle.net/10261/342119 | DOI: | 10.1080/14636778.2017.1302324 | ISSN: | 1463-6778 |
Aparece en las colecciones: | (CCHS-IPP) Artículos |
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The Politics of Biomedical Platforms-preprint.pdf | 315,99 kB | Adobe PDF | Visualizar/Abrir |
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