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http://hdl.handle.net/10400.18/6272
Título: | Respiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013-2014 |
Autor: | Chasqueira, Maria-Jesus Paixão, Paulo Rodrigues, Maria-Lúcia Piedade, Cátia Caires, Iolanda Palmeiro, Teresa Botelho, Maria-Amalia Santos, Madalena Curran, Martin Guiomar, Raquel Pechirra, Pedro Costa, Inês Papoila, Ana Alves, Marta Neuparth, Nuno |
Palavras-chave: | Elderly Aged, 80 and Over Female Follow-Up Studies Homes for the Aged Humans Male Middle Aged Nursing Homes Polymerase Chain Reaction Portugal Respiratory Tract Infections Seasons Vaccines Virus Diseases Infecções Respiratórias |
Data: | Abr-2018 |
Editora: | Elsevier/ International Society for Infectious Diseases |
Citação: | Int J Infect Dis. 2018 Apr;69:1-7. doi: 10.1016/j.ijid.2018.01.012. Epub 2018 Jan 31 |
Resumo: | Objective: The aim of this study was to analyze the etiology and clinical consequences of viral respiratory infections in 18 elderly care centers (ECC) in Lisbon, which housed a total of 1022 residents. Methods: Nasopharyngeal swabs were collected whenever an elderly had symptoms of acute respiratory infections (ARI). PCR and RT-PCR were performed for influenza A/B, human parainfluenza virus 1–4, adenovirus, human metapneumovirus (HMPV), respiratory syncytial virus (RSV), rhinovirus, enterovirus, human coronavirus and human Bocavirus (HBoV). Array cards for atypical bacteria were also used in severe cases. Results: In total, 188 episodes of ARI were reported, being rhinovirus the most frequently detected (n = 53), followed by influenza A(H3) (n = 19) and HBoV (n = 14). Severe infections were reported in 19 patients, 11 of which were fatal, Legionela pneumophila, rhinovirus, HMPV and RSV associated with these fatalities. Nine influenza strains were analyzed, all antigenically dissimilar from vaccine strain 2013/14. “Age”, “HMPV” and “Respiratory disease” showed an association with severe infection. Conclusions: In this study an etiologic agent could be found in 60% of the acute respiratory episodes. These data provides information about the circulating viruses in ECC and highlights the importance of searching both viruses and atypical bacteria in severe ARI. |
Descrição: | Supplementary data associated with this article can be found, in the online version, at https://doi.org/10.1016/j.ijid.2018.01.012. |
Peer review: | yes |
URI: | http://hdl.handle.net/10400.18/6272 |
DOI: | 10.1016/j.ijid.2018.01.012 |
ISSN: | 1201-9712 |
Versão do Editor: | https://www.sciencedirect.com/science/article/pii/S1201971218300134?via%3Dihub |
Aparece nas colecções: | DDI - Artigos em revistas internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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1-s2.0-S1201971218300134-main.pdf | 925,16 kB | Adobe PDF | Ver/Abrir |
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