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http://hdl.handle.net/10400.19/7552
Título: | Crimean-Congo hemorrhagic fever virus circulating among sheep of Portugal: a nationwide serosurvey assessment |
Autor: | Mesquita, João Cruz, Rita Esteves, Fernando Santos, Carla Pousa, Humberto Coelho, Catarina Mega, Cristina Nóbrega, Carmen Vala, Helena Peyrefitte, Christophe Nicolas Nascimento, Maria São José Barradas, Patrícia Ferreira |
Palavras-chave: | Crimean-Congo hemorrhagic fever virus ELISA Sheep |
Data: | 22-Jul-2022 |
Editora: | Sringer |
Citação: | Mesquita JR, Cruz R, Esteves F, Santos C, Pousa H, Coelho C, Mega AC, Nóbrega C, Vala H, Peyrefitte CN, Nascimento MSJ, Barradas PF. (2022). Crimean-Congo hemorrhagic fever virus circulating among sheep of Portugal: a nationwide serosurvey assessment. Troprical Animal Health and Production, 54(4):237. doi: 10.1007/s11250-022-03238-z. |
Resumo: | Crimean-Congo hemorrhagic fever virus (CCHFV) is a widespread zoonotic pathogen that can cause mild to severe hemorrhagic disease in humans. CCHFV may be transmitted through direct contact with tissue or blood of viremic animals; however, the primary transmission route is through infected tick bites. CCHFV RNA has been detected in ticks feeding on domestic and wild animals in western Spain, suggesting an established circulation of CCHFV in Western Europe. Ruminants have been recognized as important CCHFV reservoirs and have been linked to human cases in endemic regions. Given the emergence of CCHF in neighboring Spain, and a report of two CCHFV seropositive humans in southern Portugal in 1985, we investigated the potential circulation of this virus in the country by performing a nationwide anti-CCHFV IgG serosurvey in sentinel sheep of Portugal. Sera (n = 459) randomly selected from widely distributed farms (n = 20) of Portugal were tested using a commercial double-antigen enzyme-linked immunosorbent assay, yielding an overall seroprevalence of 0.4% (95% confidence interval [CI] 0.04-1.56%). Positive sheep were from the southern region of Portugal (Alentejo region), which raise the seroprevalence of this region to 0.74% (95% CI 0.09-2.66%). This is the first study reporting the presence of CCHFV antibodies in sheep of Portugal, thus suggesting a geographical expansion of CCHFV to this country. It seems likely that CCHFV may exist focally in southern Portugal. |
Peer review: | yes |
URI: | http://hdl.handle.net/10400.19/7552 |
DOI: | doi: 10.1007/s11250-022-03238-z |
Aparece nas colecções: | ESAV - DZERV - Artigo em revista científica, indexada ao WoS/Scopus CERNAS - Artigo em revista científica, indexada ao WoS/Scopus |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Barradas et al. 2022. Crimean-Congo hemorrhagic fever virus circulating among sheep of Portugal.pdf | 1,2 MB | Adobe PDF | Ver/Abrir Acesso Restrito. Solicitar cópia ao autor! |
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