Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10400.6/9026
Título: | Environmental risk factors associated with biliary atresia in Rio Grande do sul, Brazil |
Autor: | Longo, Larisse Ferrari, Jéssica Tonin Hoss, Giovana Regina Weber Fratta, Leila Xavier Sinigaglia Vieira, Sandra Maria Gonçalves Silveira, Themis Reverbel da Silva, Fernando Antônio de Abreu e Sanseverino, Maria Teresa Santos, Jorge Luiz dos |
Palavras-chave: | Biliary atresia Environmental risk factor Etiology Seasonality Smoking |
Data: | 2017 |
Resumo: | Biliary atresia (BA) seems to be a multifactorial disorder in which environmental factors interact with the patient’s genetic constitution. This study aimed to analyze information concerning environmental risk factors associated with BA in southern Brazil. A case-control study with mothers of patients with BA and mothers of patients with cystic fibrosis (CF) was conducted. Inquiry included questions related to exposition to environmental risk factors during the periconceptional and gestational (second and third trimesters) periods. Mothers of BA patients had smoked during pregnancy more frequently in comparison with the mothers of CF patients, but no significant difference was found in a multivariate analysis. There was no between group difference in terms of seasonality, but the multivariate analysis showed a significant difference within the BA group between date of conception in winter compared to other seasons. In conclusion, smoking during pregnancy seemed to increase the risk of BA while date of conception in winter decreased it. |
Peer review: | yes |
URI: | http://hdl.handle.net/10400.6/9026 |
DOI: | 10.4322/2357-9730.71572 |
Aparece nas colecções: | FCS - DCM | Documentos por Auto-Depósito |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Fatores de risco ambientais de atresia biliar RS.pdf | 740,1 kB | Adobe PDF | Ver/Abrir |
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