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http://hdl.handle.net/10400.8/6653
Título: | Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study |
Autor: | Duarte, Catia Carvalheiro, Helena Rodrigues, Ana M. Dias, Sara S. Marques, Andréa Santiago, Tânia Canhão, Helena Branco, Jaime Cunha Silva, José António Pereira da |
Palavras-chave: | Vitamin D Prevalence Portugal 25-hydroxyvitamin D Vitamin D deficiency Vitamin D insufficiency |
Data: | 2020 |
Editora: | Springer |
Citação: | Duarte, C., Carvalheiro, H., Rodrigues, A. M., Dias, S. S., Marques, A., Santiago, T., Canhão, H., Branco, J. C., & da Silva, J. A. P. (2020). Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study (Archives of Osteoporosis, (2020), 15, 1, (36), 10.1007/s11657-020-0695-x). Archives of Osteoporosis, 15(1), [55]. https://doi.org/10.1007/s11657-020-00728-1 |
Resumo: | Summary Vitamin D deficiency is prevalent worldwide, but its prevalence is unknown in adult Portuguese population. In Portugal, 66% of adults present Vitamin D insufficiency/deficiency. Winter, living in Azores, older age, and obesity were the most important risk factors. It highlights the need of strategies to prevent vitamin D deficiency in Portugal. Objective To estimate the prevalence and risk factors of vitamin D deficiency in the adult Portuguese population. Methods Adults (≥ 18 years old) from the EpiReumaPt Study (2011–2013) were included. Standardized questionnaires on sociodemographic and lifestyle features were obtained. Serum 25-hydroxyvitamin D [25(OH)D] concentrations were evaluated using ADVIA Centaur VitD competitive immunoassay (Siemens Healthineers) in 2015–2017 as 25 (OH)D Level 0: ≤ 10 ng/mL; Level 1: 11–19 ng/mL; Level 2: 20–29 ng/mL, and Level 3: ≥ 30 ng/mL. Weighted multinomial regression analysis was conducted to evaluate the association between socio-demographic and lifestyle variables and vitamin D status. Results Based on weighted analysis, the estimated prevalence of levels of 25(OH)D ≤ 10, < 20, and < 30 ng/mL was 21.2, 66.6, and 96.4%, respectively. The strongest independent predictors of serum 25 (OH)D ≤ 10 ng/mL were living in the Azores archipelagos (OR 9.39; 95%CI 1.27–69.6) and having the blood sample collection in winter (OR 18.53; 95%CI 7.83–43.87) or spring (11.55; 95%CI 5.18–25.74). Other significant predictors included older age (OR 5.65, 95%CI 2.08–15.35), obesity (OR 2.61; 95%CI 1.35–5.08), current smoking (OR 2.33; 95%CI 1.23–4.43), and female gender (OR 1.9, 95%CI 1.1–3.28). Conversely, physical exercise (OR 0.48, 95%CI 0.28–0.81) and occasional alcohol intake (OR 0.48, 95%CI 0.29–0.81) were associated with a lower risk of 25(OH)D ≤ 10 ng/mL. Conclusion Vitamin D deficiency/insufficiency [25(OH)D < 20 ng/ml] is highly prevalent in Portugal, affecting > 60% of all Portuguese adults, with strong geographical and seasonal variation. This study highlights the need to critically assess the relevance of vitamin D deficiency as a public health problem and the urgent need for a wide and scientifically robust debate about the most appropriate interventions at the individual and societal levels. |
Peer review: | yes |
URI: | http://hdl.handle.net/10400.8/6653 |
DOI: | 10.1007/s11657-020-00728-1 |
ISSN: | 1862-3514 |
Versão do Editor: | https://link.springer.com/article/10.1007/s11657-020-0695-x |
Aparece nas colecções: | ESSLei - Artigos em revistas internacionais ciTechCare - Artigos |
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Ficheiro | Descrição | Tamanho | Formato | |
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Prevalence of vitamin D deficiency and its predictors in the Portuguese population_ a nationwide population-based study.pdf | 503,48 kB | Adobe PDF | Ver/Abrir Acesso Restrito. Solicitar cópia ao autor! |
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