Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: Preliminary data

Stelzer-Braid, S; Liu, N; Doumit, M; D'Cunha, R; Belessis, Y; Jaffe, A; Rawlinson, WD

Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: Preliminary data

Stelzer-Braid, S

Liu, N Doumit, M D'Cunha, R Belessis, Y Jaffe, A Rawlinson, WD

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Publication Type:: Journal Article
Citation:: Journal of Medical Virology, 2017, 89 (8), pp. 1494 - 1497
Issue Date:: 2017-08-01

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Field	Value	Language
dc.contributor.author	Stelzer-Braid, S https://orcid.org/0000-0001-6037-9305	en_US
dc.contributor.author	Liu, N	en_US
dc.contributor.author	Doumit, M	en_US
dc.contributor.author	D'Cunha, R	en_US
dc.contributor.author	Belessis, Y	en_US
dc.contributor.author	Jaffe, A	en_US
dc.contributor.author	Rawlinson, WD	en_US
dc.date.available	2017-02-09	en_US
dc.date.issued	2017-08-01	en_US
dc.identifier.citation	Journal of Medical Virology, 2017, 89 (8), pp. 1494 - 1497	en_US
dc.identifier.issn	0146-6615	en_US
dc.identifier.uri	http://hdl.handle.net/10453/114901
dc.description.abstract	© 2017 Wiley Periodicals, Inc. Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.	en_US
dc.relation.ispartof	Journal of Medical Virology	en_US
dc.relation.isbasedon	10.1002/jmv.24794	en_US
dc.subject.classification	Virology	en_US
dc.subject.mesh	Respiratory System	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Rhinovirus	en_US
dc.subject.mesh	Respiratory Tract Infections	en_US
dc.subject.mesh	Picornaviridae Infections	en_US
dc.subject.mesh	Cystic Fibrosis	en_US
dc.subject.mesh	RNA, Viral	en_US
dc.subject.mesh	Polymerase Chain Reaction	en_US
dc.subject.mesh	Reverse Transcriptase Polymerase Chain Reaction	en_US
dc.subject.mesh	Air Microbiology	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Child	en_US
dc.subject.mesh	Child, Preschool	en_US
dc.subject.mesh	Infant	en_US
dc.subject.mesh	Infant, Newborn	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.title	Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: Preliminary data	en_US
dc.type	Journal Article
utslib.citation.volume	8	en_US
utslib.citation.volume	89	en_US
utslib.for	1108 Medical Microbiology	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	0801 Artificial Intelligence and Image Processing	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	closed_access
pubs.issue	8	en_US
pubs.publication-status	Published	en_US
pubs.volume	89	en_US

Abstract:

© 2017 Wiley Periodicals, Inc. Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years). RV particles were detected in the air of clinic rooms. Detection of RV is important in better understanding viral infections in patients with CF.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/114901