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EAACI Biologicals Guidelines-dupilumab for children and adults with moderate-to-severe atopic dermatitis


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Título : EAACI Biologicals Guidelines-dupilumab for children and adults with moderate-to-severe atopic dermatitis
Autor : Agache, Ioana
Akdis, Cezmi A.
Akdis, Mubeccel
Brockow, Knut
Chivato Pérez, Tomás
Giacco, Stefano del
Eiwegger, Thomas
Eyerich, Kilian
Giménez Arnau, Ana
Gutermuth, Jan
Guttman-Yassky, Emma
Maurer, Marcus
Ong, Peck Y.
O'Mahony, Liam
Schwarze, Jürgen
Warner, Amena
Werfel, Thomas
Jutel, Marek
Ogg, Graham
Palomares, Oscar
Materias: Atopic dermatitisDupilumabGRADEGuideline
Editorial : Wiley
Citación : Agache, I., Akdis, C., Akdis, M., Brockow, K., Chivato, T., Del Giacco, S., Eiwegger, T., Eyerich, K., Giménez- Arnau, A., Gutermuth, J., Guttman-Yassky, E., Maurer, M., Ogg, G., Ong, P. Y., O'Mahony, L., Schwarze, J., Warner, A., Werfel, T., Palomares, O., & Jutel, M. (2021). EAACI Biologicals Guidelines-dupilumab for children and adults with moderate-to-severe atopic dermatitis. Allergy, 76(4), 988-1009. https://doi.org/10.1111/all.14690
Resumen : Atopic dermatitis imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity, comorbidities, complexity in care pathways and differences between national or regional healthcare systems. Better understanding of the mechanisms has enabled a stratified approach to the management of atopic dermatitis, supporting the use of targeted treatments with biologicals. However, there are still many issues that require further clarification. These include the definition of response, strategies to enhance the responder rate, the duration of treatment and its regimen (in the clinic or home-based), its cost-effectiveness and long-term safety. The EAACI Guidelines on the use of dupilumab in atopic dermatitis follow the GRADE approach in formulating recommendations for each outcome and age group. In addition, future approaches and research priorities are discussed.
URI : http://hdl.handle.net/10637/15132
Derechos: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
ISSN : 1398-9995
Fecha de publicación : abr-2021
Centro : Universidad San Pablo-CEU
Aparece en las colecciones: Medicina





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