Allele frequencies of three forensic STR markers (D22S1045, D2S441 and D10S1248) in the population from Sao Paulo, Brazil
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2017-12-01
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Elsevier B.V.
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Sao Paulo state is one of the Brazilian states with the highest cultural and ethnic miscegenation, mainly of Italian and Portuguese descendants, but also strongly influenced by Amerindians, Africans, Spanish, Germans, Arabs and Japanese, as well as the high number of immigrants from the northeast region. In this work we analyzed statistical data of three STRs markers (D22S1045, D2S441 and D10S1248) that are used in our laboratory's forensic routine for paternity investigations. The use of these data will be extremely important for the laboratory to perform statistical analyzes for the conclusion of the reports. We analyzed 221 samples obtained from unrelated individuals born in the Sao Paulo state, which the allele frequencies and statistical parameters were estimated with PowerStats version 12 (Promega Corp.). The power of discrimination (PD) and power of exclusion (PE) for the D10S1248 marker were 0.914 and 0.576 respectively and the allele 14 showed the highest frequency (0.294) and 8, 10, 18 and 19 alleles presented the lowest frequency (0.002). PD and PE of the D2S441 marker were 0.907 and 0.551 respectively; the highest frequency allele was 11 (0.312) and the lowest frequency alleles were 9 and 12.3 (0.002). The marker D22S1045 showed PD 0.890 and PE 0.489 with a higher frequency allele 16 (0.373) and lowest frequency allele 8 (0.002). Also, significant differences were found between the Sao Paulo population and the other populations for the three markers analyzed.
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Forensic Science International Genetics Supplement Series. Clare: Elsevier Ireland Ltd, v. 6, p. E296-E297, 2017.