Optoelectronic holographic otoscope for measurement of nano-displacements in tympanic membranes
Author(s)
Rosowski, John J.; Furlong, Cosme; Santoyo, Fernando Mendoza; Ravicz, Michael E.; Cheng, Jeffrey Tao; Harrington, Ellery; Hulli, Nesim; Hernández-Montes, Maria del Socorro; Santoyo, Fernando Mendoza; ... Show more Show less
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Current methodologies for characterizing tympanic membrane (TM) motion are usually limited to either average acoustic estimates (admittance or reflectance) or single-point mobility measurements, neither of which suffices to characterize the detailed mechanical response of the TM to sound. Furthermore, while acoustic and single-point measurements may aid in diagnosing some middle-ear disorders, they are not always useful. Measurements of the motion of the entire TM surface can provide more information than these other techniques and may be superior for diagnosing pathology. We present advances in our development of a new compact optoelectronic holographic otoscope (OEHO) system for full field-of-view characterization of nanometer-scale sound-induced displacements of the TM surface at video rates. The OEHO system consists of a fiber optic subsystem, a compact otoscope head, and a high-speed image processing computer with advanced software for recording and processing holographic images coupled to a computer-controlled sound-stimulation and recording system. A prototype OEHO system is in use in a medical research environment to address basic science questions regarding TM function. The prototype provides real-time observation of sound-induced TM displacement patterns over a broad frequency range. Representative time-averaged and stroboscopic holographic interferometry results in animals and human cadaver samples are shown, and their potential utility is discussed.
Date issued
2009-06Department
Harvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Research Laboratory of ElectronicsJournal
Journal of Biomedical Optics
Publisher
Society of Photo-Optical Instrumentation Engineers
Citation
Hernandez-Montes, Maria del Socorro et al. “Optoelectronic holographic otoscope for measurement of nano-displacements in tympanic membranes.” Journal of Biomedical Optics 14.3 (2009): 034023-9. © 2009 Society of Photo-Optical Instrumentation Engineers
Version: Final published version