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http://hdl.handle.net/1843/52439| Type: | Artigo de Periódico |
| Title: | Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the global burden of disease study 2016 |
| Authors: | Christophertroeger Zegeye Abebe Juan Ramon Sanabria Benn Sartorius Monika Sawhney Sadaf g Sepanlou Mika Shigematsu Mekonnen Sisay Ranjani Somayaji Chandrashekhar t Sreeramareddy Bryan l Sykes Nancy Fullman Peter w Gething Melkamu Dedefo Gishu William w Godwin Harish Chander Gugnani Shujin Cao Rahul Gupta Gessessew Bugssa Hailu Hamid Yimam Hassen Desalegn Tsegaw Hibstu Suresh Mehata Olayinka s Ilesanmi Jost b Jonas Amaha Kahsay Gagandeep Kang Amir Kasaeian Yousef Saleh Khader Stephanie rm Zimsen Ibrahim a Khalil Ejaz Ahmad Khan Muhammad Ali Khan Walter Mendoza Young-ho Khang Niranjan Kissoon Sonali Kochhar Karen l Kotloff ai Koyanagi g Anil Kumar Hassan Magdy Abd el Razek Samuel b Albertson Reza Malekzadeh Deborah Carvalho Malta Desalegn Tadese Mengistu Bereket Gebremichael Menota Haftay Berhane Mezgebe Fitsum Weldegebreal Mlashu Srinivas Murthy Gurudatta a Naik Jeffery d Stanaway Cuong Tat Nguyen Getachew Redae Taffere Trang Huyen Nguyen Dina Nur Anggraini Ningrum Felix Akpojene Ogbo Andrew Toyin Olagunju Deepak Paudel James a Platts-mills Mostafa Qorbani Anwar Rafay Rajesh Kumar Rai Aniruddha Deshpande Nelson Alvis-guzman Saleem m Rana Chhabi Lal Ranabhat Davide Rasella Sarah e Ray Cesar Reis Andre mn Renzaho Mohammad Sadegh Rezai George Mugambage Ruhago Saeid Safiri Joshua a Salomon Roman Topor-madry Bach Xuan Tran Kald Beshir Tuem Kingsley Nnanna Ukwaja Stein Emil Vollset Judd l Walson Marcia r Weaver Kidu Gidey Weldegwergs Andrea Werdecker Abdulhalik Workicho Azmeraw t Amare Muluken Yenesew Biruck Desalegn Yirsaw Naohiro Yonemoto Maysaa el Sayed Zaki Theo Vos Stephen s Lim Mohsen Naghavi Christopher jl Murray Ali h Mokdad Simon i Hay Solomon w Asgedom Robert c Reiner Zelalem Alamrew Anteneh Carl Abelardo t Antonio Olatunde Aremu Ephrem Tsegay Asfaw Tesfay Mehari Atey Suleman Atique Brigette f Blacker Euripide Frinel g Arthur Avokpaho Ashish Awasthi Henok Tadesse Ayele Aleksandra Barac Mauricio l Barreto Quique Bassat Saba Abraham Belay Isabela m Bensenor Zulfiqar a Bhutta Ali Bijani Ibrahim a Khalil Hailemichael Bizuneh Carlos a Castañeda-orjuela Abel Fekadu Dadi Lalit Dandona Rakhi Dandona Huyen Phuc do Manisha Dubey Eleonora Dubljanin Dumessa Edessa Aman Yesuf Endries Puja c Rao Babak Eshrati Tamer Farag Garumma Tolu Feyissa Kyle j Foreman Mohammad h Forouzanfar |
| Abstract: | Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 provides an up-to-date analysis of the burden of diarrhoea in 195 countries. This study assesses cases, deaths, and aetiologies in 1990–2016 and assesses how the burden of diarrhoea has changed in people of all ages.Methods We modelled diarrhoea mortality with a Bayesian hierarchical modelling platform that evaluates a wide range of covariates and model types on the basis of vital registration and verbal autopsy data. We modelled diarrhoea incidence with a compartmental meta-regression tool that enforces an association between incidence and prevalence, and relies on scientific literature, population representative surveys, and health-care data. Diarrhoea deaths and episodes were attributed to 13 pathogens by use of a counterfactual population attributable fraction approach. Diarrhoea risk factors are also based on counterfactual estimates of risk exposure and the association between the risk and diarrhoea. Each modelled estimate accounted for uncertainty.Findings In 2016, diarrhoea was the eighth leading cause of death among all ages (1 655944 deaths, 95% uncertainty interval [UI] 1244 073–2366 552) and the fifth leading cause of death among children younger than 5 years (446 000 deaths, 390 894–504 613). Rotavirus was the leading aetiology for diarrhoea mortality among children younger than 5 years (128 515 deaths, 105138–155 133) and among all ages (228 047 deaths, 183 526–292737). Childhood wasting (low weight-for-height score), unsafe water, and unsafe sanitation were the leading risk factors for diarrhoea, responsible for 80·4% (95% UI 68·2–85·0), 72·1% (34·0–91·4), and 56·4% (49·3–62·7) of diarrhoea deaths in children younger than 5 years, respectively. Prevention of wasting in 1762 children (95% UI 1521–2170) could avert one death from diarrhoea. Interpretation Substantial progress has been made globally in reducing the burden of diarrhoeal diseases, driven by decreases in several primary risk factors. However, this reduction has not been equal across locations, and burden among adults older than 70 years requires attention. |
| Subject: | Mortalidade Carga Viral de Doença Epidemiologia |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1016/s1473-3099(18)30362-1 |
| URI: | http://hdl.handle.net/1843/52439 |
| Issue Date: | 2018 |
| metadata.dc.url.externa: | https://doi:10.1016/s1473-3099(18)30362-1 |
| metadata.dc.relation.ispartof: | The Lancet |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Estimates of the global,regionala, and national morbidity,mortality, and aetiologies of diarrhoea in 195 countries pdfa.pdf | 1.14 MB | Adobe PDF | View/Open |
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