Amino Acid Transporters as Targets for Cancer Therapy: Why, Where, When, and How
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Description
Amino acids are indispensable for the growth of cancer cells. This includes essential amino acids, the carbon skeleton of which cannot be synthesized, and conditionally essential amino acids, for which the metabolic demands exceed the capacity to synthesize them. Moreover, amino acids are important signaling molecules regulating metabolic pathways, protein translation, autophagy, defense against reactive oxygen species, and many other functions. Blocking uptake of amino acids into cancer cells...[Show more]
Collections | ANU Research Publications |
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Date published: | 2020 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/222887 |
Source: | International Journal of Molecular Sciences |
DOI: | 10.3390/ijms21176156 |
Access Rights: | Open Access |
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File | Description | Size | Format | Image |
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01_Broer_Amino_Acid_Transporters_as_2020.pdf | 1.43 MB | Adobe PDF |
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