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Application of PVA – GTA Fricke gel detectors and Gafchromic ™ EBT3 Ballcube I dosimetric films for the analysis of blocked radiation beams in the Gamma Knife® technique

Katarzyna Antończyk-Szewczyk

Abstract

Radiotherapy, which uses the energy of ionizing radiation, is one of the methods of local treatment of both malignant and benign tumors. Technological development helps to improve this method of treatment both in the field of radiotherapy equipment and treatment planning systems. The improvement of working tools and the introduction of new, advanced irradiation techniques make it possible to deliver a given dose to the target area with increasingly better precision. The main research objective of this dissertation is to analyze the dose distributions of blocked radiation beams in the LGK PFX technique. Blocked beams effectively minimize the dose to organs at risk, among others, during the trigeminal neuralgia treatment. The study was performed using Gafchromic™ EBT3 Ballcube I dosimetric films and gel detectors. The use of a new type of gel detector based on Fricke gel PVA - GTA was possible through cooperation with a scientific foreign center engaged in the production of various types of detectors for clinical dosimetry. The irradiation of some gel detectors and the graphical analysis of all irradiated gel detectors were performed in collaboration with the Katowice Oncology Center. The study was conducted in several stages. An important part of this dissertation was the development of optimal operating conditions for the gel detectors used in the LGK PFX technique. In addition, individual phantoms were prepared and used during the irradiation of gel detectors and dosimetry films. This study used two devices applied in radiotherapy: the LGK PFX and a linear accelerator. Nine treatment plans that included the most commonly used systems of interlocked sectors in beams for the treatment of trigeminal neuralgia and their hybrid plans were analyzed. The objectives set in the dissertation were achieved. The applied detectors allowed for a very detailed analysis of the obtained dose distributions, mainly in terms of the effects specific to the blocked beams. Very promising results were obtained when using the Fricke gel PVA - GTA detector in clinical dosimetry for LGK PFX.
Record ID
USL66ccacad2e7c4e579bc88a0622c0c0ab
Diploma type
Doctoral Degree
Author
Title in Polish
Zastosowanie detektorów żelowych Fricke gel PVA – GTA oraz filmów dozymetrycznych Gafchromic™ EBT3 Ballcube I do analizy blokowanych ekspozycji promieniowania w technice Gamma Knife®
Title in English
Application of PVA – GTA Fricke gel detectors and Gafchromic ™ EBT3 Ballcube I dosimetric films for the analysis of blocked radiation beams in the Gamma Knife® technique
Language
pol (pl) Polish
Certifying Unit
Faculty of Science and Technology (FST)
Scientific discipline (2.0)
physical sciences (PS)
Status
Finished
Year of creation
2021
Start date
15-05-2018
Defense Date
21-06-2021
Supervisor
External reviewers
Maciej Budzanowski Maciej Budzanowski,, Undefined Affiliation
Tomasz Piotrowski Tomasz Piotrowski,, Undefined Affiliation
Pages
202
License
Open licence other than CC
Handle.net URL
hdl.handle.net/20.500.12128/20427 Opening in a new tab
URL
https://integro.ciniba.edu.pl/integro/193208022081 Opening in a new tab
Keywords in English
Gamma Knife; stereotactic radiosurgery; blocked radiation beams; Fricke gel PVA - GTA detectors; Gafchromic™ EBT3 Ballcube I films
Abstract in English
Radiotherapy, which uses the energy of ionizing radiation, is one of the methods of local treatment of both malignant and benign tumors. Technological development helps to improve this method of treatment both in the field of radiotherapy equipment and treatment planning systems. The improvement of working tools and the introduction of new, advanced irradiation techniques make it possible to deliver a given dose to the target area with increasingly better precision. The main research objective of this dissertation is to analyze the dose distributions of blocked radiation beams in the LGK PFX technique. Blocked beams effectively minimize the dose to organs at risk, among others, during the trigeminal neuralgia treatment. The study was performed using Gafchromic™ EBT3 Ballcube I dosimetric films and gel detectors. The use of a new type of gel detector based on Fricke gel PVA - GTA was possible through cooperation with a scientific foreign center engaged in the production of various types of detectors for clinical dosimetry. The irradiation of some gel detectors and the graphical analysis of all irradiated gel detectors were performed in collaboration with the Katowice Oncology Center. The study was conducted in several stages. An important part of this dissertation was the development of optimal operating conditions for the gel detectors used in the LGK PFX technique. In addition, individual phantoms were prepared and used during the irradiation of gel detectors and dosimetry films. This study used two devices applied in radiotherapy: the LGK PFX and a linear accelerator. Nine treatment plans that included the most commonly used systems of interlocked sectors in beams for the treatment of trigeminal neuralgia and their hybrid plans were analyzed. The objectives set in the dissertation were achieved. The applied detectors allowed for a very detailed analysis of the obtained dose distributions, mainly in terms of the effects specific to the blocked beams. Very promising results were obtained when using the Fricke gel PVA - GTA detector in clinical dosimetry for LGK PFX.
Thesis file
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RDF
Uniform Resource Identifier
https://opus.us.edu.pl/info/phd/USL66ccacad2e7c4e579bc88a0622c0c0ab/
URN
urn:uni-kat-prod:USL66ccacad2e7c4e579bc88a0622c0c0ab
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