Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/23493
Title: | FLOW CYTOMETRY DIAGNOSIS OF (CD4+/CD8+) T CELL LYMPHOBLASTIC LEUKEMIA ASSOCIATED WITH NORMAL KARYOTYPE - CASE REPORT | Authors: | Trajkova, Sanja Chevrevska, Lidija Ivanovski, Martin Dukovski, Dushko Simjanovska-Popova, Marija Panovska Stavridis, Irina |
Keywords: | T-cell Acute Lymphoblastic Leukemia flow cytometry cerebrospinal fluid |
Issue Date: | Apr-2013 | Publisher: | Radiance Research Academy | Journal: | International Journal of Current Research and Review | Abstract: | Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell neoplasm caused by human T-cell lymphotropic virus type I (HTLV-I). The neoplastic cells are highly pleomorphic and are usually CD4+ and CD8- phenotypically, but some rare cases have unusual immmunophenotype presented by co-expression of CD4/CD8 double positive cells. We present a rare case of a patient with T cell lymphoblastic leukemia associated with double-positive (CD4+/CD8+) blast cells. The diagnose was accessed with multiparameter immunophenotyping by flow cytometry analyses of bone marrow, and for the first time in our country, we confirmed isolated relapse of double-positive (CD4+/CD8+) T cell lymphoblastic leukemia in CNS | URI: | http://hdl.handle.net/20.500.12188/23493 |
Appears in Collections: | Faculty of Medicine: Journal Articles |
Files in This Item:
File | Description | Size | Format | |
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Flow Sanja Trajkova.pdf | 484.66 kB | Adobe PDF | View/Open |
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