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Mécanisme d'action, indications et abus des benzodiazépines anxiolytiques.

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Goffinet, S.

Anxiolytic benzodiazepines are used in the treatment of anxiety. Nonmedical use has widely developed, mainly because of their ability to generate addiction. Main indications are anxiety disorders with or without depressive symptoms. Action mechanisms include complex interaction with GABA-receptor. Dependence, tolerance and withdrawal are well-known. Treatment of substance abuse is given. Main non-benzodiazepine alternate treatments of anxiety disorders are proposed.

Document type Article de périodique (Journal article) – English Abstract, Journal Article, Review
Publication date 1993
Journal information "Annales médico-psychologiques" - Vol. 151, no. 1, p. 47-63 (1993)
Peer reviewed yes
issn 0003-4487
Publication status Publié
Affiliation UCL
MESH Subject Anti-Anxiety Agents - adverse effects - therapeutic use ; Anxiety Disorders - drug therapy - physiopathology - psychology ; Brain - drug effects - physiopathology ; Depressive Disorder - drug therapy - physiopathology - psychology ; Humans ; Neurotransmitter Agents - physiology ; Receptors, GABA-A - drug effects - physiology ; Substance-Related Disorders - etiology - physiopathology - rehabilitation
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Bibliographic reference Goffinet, S.. Mécanisme d'action, indications et abus des benzodiazépines anxiolytiques.. In: Annales médico-psychologiques, Vol. 151, no. 1, p. 47-63 (1993)
Permanent URL http://hdl.handle.net/2078.1/11959