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Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.

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de Meester, Carole Timmermans, Aurélie [UCL] Balteau, Magali [UCL] Ginion, Audrey Roelants, Véronique Porporato, Paolo [UCL] Sonveaux, Pierre [UCL] Feron, Olivier [UCL] Horman, Sandrine [UCL] Vanoverschelde, Jean-Louis [UCL] Bertrand, Luc [UCL]

MSCs resist hypoxia independently of AMPK whereas chronic AMPK activation inhibits MSC proliferation, p27 being involved in this regulation.

Document type Article de périodique (Journal article)
Publication date 2014
Language Anglais
Journal information "Cardiovascular Research" - Vol. 101, no. 1, p. 20-29 (2014)
Peer reviewed yes
Publisher Oxford University Press ((United Kingdom) Oxford)
issn 0008-6363
e-issn 1755-3245
Publication status Publié
Affiliations UCL - SSS/IREC - Institut de recherche expérimentale et clinique
UCL - SSS/IREC/CARD-Pôle de recherche cardiovasculaire
UCL - (SLuc) Service de cardiologie
UCL - SSS/IREC/FATH - Pôle de Pharmacologie et thérapeutique
Links
Bibliographic reference de Meester, Carole ; Timmermans, Aurélie ; Balteau, Magali ; Ginion, Audrey ; Roelants, Véronique ; et. al. Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.. In: Cardiovascular Research, Vol. 101, no. 1, p. 20-29 (2014)
Permanent URL http://hdl.handle.net/2078.1/137079