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Sodium polystyrene sulfonate: still news after 60 years on the market.

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Labriola, Laura [UCL] Jadoul, Michel [UCL]

(eng) yperkalaemia is common and potentially life-threatening in multiple clinical settings, especially in chronic kidney disease (CKD). Potassium-binding resins (K resins) have been used for 60 years for the treatment of hyperkalaemia. Sodium polystyrene sulfonate (SPS) is a cross-linked polymer whose reactive sulfonic groups exchange preloaded sodium (Na) for another cation. As a result of the concentrations of Na+ and K+ along the gastrointestinal (GI) lumen, the single favourable site for Na+–K+ exchange is the colon. [...]

Document type Article de périodique (Journal article) – Éditorial
Access type Accès libre
Publication date 2020
Language Anglais
Journal information "Nephrology, dialysis, transplantation" - Vol. 35, no. 9, p. 1455-1458 (2020)
Peer reviewed yes
Publisher Oxford University Press ((United Kingdom) Oxford)
issn 0931-0509
e-issn 1460-2385
Publication status Accepté/Sous presse
Affiliations UCL - SSS/IREC/NEFR - Pôle de Néphrologie
UCL - (SLuc) Service de néphrologie
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Bibliographic reference Labriola, Laura ; Jadoul, Michel. Sodium polystyrene sulfonate: still news after 60 years on the market.. In: Nephrology, dialysis, transplantation, Vol. 35, no. 9, p. 1455-1458 (2020)
Permanent URL http://hdl.handle.net/2078.1/229306