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Hypothyroidism and arthritis during interferon therapy.

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D'Hondt, Lionel [UCL] Delannoy, A Docquier, C

The development of autoantibodies during interferon therapy is frequent, but clinical symptoms of autoimmune disease are uncommon. We report on a female patient who developed arthritis with strongly positive antinuclear factor (ANA) and autoimmune thyroiditis while being treated with alpha 2b interferon (IFN) for chronic myelocytic leukaemia (CML). The arthritis subsided promptly after discontinuation of IFN and initiation of nonsteroidal anti-inflammatory drugs.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès libre
Publication date 1993
Language Anglais
Journal information "Clinical rheumatology" - Vol. 12, no. 3, p. 415-7 (1993)
Peer reviewed yes
issn 0770-3198
Publication status Publié
Affiliations UCL - SSS/IREC/MONT - Pôle Mont Godinne
UCL - (MGD) Service d'oncologie médicale
MESH Subject Antibodies, Antinuclear ; Arthritis ; Autoimmune Diseases ; Female ; Humans ; Hydroxyurea ; Hypothyroidism ; Interferons ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; Middle Aged ; Thyroiditis
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Bibliographic reference D'Hondt, Lionel ; Delannoy, A ; Docquier, C. Hypothyroidism and arthritis during interferon therapy.. In: Clinical rheumatology, Vol. 12, no. 3, p. 415-7 (1993)
Permanent URL http://hdl.handle.net/2078.1/246516