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      Identification of Spongionella compounds as cyclosporine A mimics

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      Manuscript.doc (4.394Mb)
      Publication date
      05/2016
      Author
      Sánchez, Jon Andoni
      Alfonso, Amparo
      Leirós, Marta
      Alonso, Eva
      Rateb, Mostafa E.
      Jaspars, Marcel
      Houssen, Wael E.
      Ebel, Rainer
      Tabudravu, J.
      Botana, Luís M.
      Keywords
      calcineurin
      NFATc1
      lymphocyte
      Spongionella
      cyclophilin A
      IL-2
      RM Therapeutics. Pharmacology
      Metadata
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      Citation
      Sánchez , J A , Alfonso , A , Leirós , M , Alonso , E , Rateb , M E , Jaspars , M , Houssen , W E , Ebel , R , Tabudravu , J & Botana , L M 2016 , ' Identification of Spongionella compounds as cyclosporine A mimics ' , Pharmacological Research , vol. 107 , pp. 407-414 . https://doi.org/10.1016/j.phrs.2016.03.029
      Publication
      Pharmacological Research
      Status
      Peer reviewed
      DOI
      https://doi.org/https://doi.org/10.1016/j.phrs.2016.03.029
      ISSN
      1043-6618
      Type
      Journal article
      Description
      Acknowledgements The research leading to these results has received funding from the following FEDER cofounded-grants. From CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R, and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016, and through Axencia Galega de Innovación, Spain, ITC-20133020 SINTOX. From CDTI under ISIP Programme, Spain, IDI-20130304 APTAFOOD. From the European Union’s Seventh Framework Programme managed by REA—Research Executive Agency (FP7/2007-2013) under grant agreement 312184 PHARMASEA. We wish to thank the Clínica Losada Arránz, especially Ms. Paula López Arránz for providing the human blood samples for T cells purification. Jon Andoni Sánchez is supported by a fellowship from Plan Galego de Investigación e Crecemento, Xunta de Galicia, Spain.
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      • Chemistry research
      • Medical Sciences research
      • University Office research
      URI
      http://hdl.handle.net/2164/8589

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