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      A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives

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      Paolo_Lazzari_reviewed_Manuscript.docx (873.7Kb)
      Publication date
      04/10/2016
      Author
      Lazzari, Paolo
      Distinto, Rita
      Manca, Ilaria
      Baillie, Gemma
      Murineddu , Gabriele
      Pira, Marilena
      Falzoi, Matteo
      Sani, Monica
      Morales, Paula
      Ross, Ruth
      Zanda, Matteo
      Jagerovic , Nadine
      Pinna, Gerard Aime
      Keywords
      cannabinoids
      endocannabinoid system (ECS)
      8-chloro-1-(2’,4’-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide
      cannabinoid receptor binding assays
      CB1 receptor ligands
      QH301 Biology
      Metadata
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      Citation
      Lazzari , P , Distinto , R , Manca , I , Baillie , G , Murineddu , G , Pira , M , Falzoi , M , Sani , M , Morales , P , Ross , R , Zanda , M , Jagerovic , N & Pinna , G A 2016 , ' A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives ' , European Journal of Medicinal Chemistry , vol. 121 , pp. 194-208 . https://doi.org/10.1016/j.ejmech.2016.05.011
      Publication
      European Journal of Medicinal Chemistry
      Status
      Peer reviewed
      DOI
      https://doi.org/https://doi.org/10.1016/j.ejmech.2016.05.011
      ISSN
      0223-5234
      Type
      Journal article
      Description
      We thank European Commission (project “PET BRAIN: Mapping the brain with PET radiolabeled cannabinoid CB1 ligands”; FP7-People-2009-IAPP; Grant Agreement N.25142).
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      • Biological Sciences research
      • Medical Sciences research
      • University Office research
      URI
      http://hdl.handle.net/2164/8608

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