Relevance of the extraction stage on the anti-inflammatory action of fucoidans
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Relevance of the extraction stage on the anti-inflammatory action of fucoidansAutor(es)
Data
2023-03-01Cita bibliográfica
Flórez-Fernández N, Vaamonde-García C, Torres MD, Buján M, Muíños A, Muiños A, Lamas-Vázquez MJ, Meijide-Faílde R, Blanco FJ, Domínguez H. Relevance of the extraction stage on the anti-inflammatory action of fucoidans. Pharmaceutics. 2023 Mar 1;15(3):808
Resumo
[Abstract] The anti-inflammatory action of fucoidans is well known, based on both in vitro and some in vivo studies. The other biological properties of these compounds, their lack of toxicity, and the possibility of obtaining them from a widely distributed and renewable source, makes them attractive novel bioactives. However, fucoidans' heterogeneity and variability in composition, structure, and properties depending on seaweed species, biotic and abiotic factors and processing conditions, especially during extraction and purification stages, make it difficult for standardization. A review of the available technologies, including those based on intensification strategies, and their influence on fucoidan composition, structure, and anti-inflammatory potential of crude extracts and fractions is presented.
Palabras chave
Brown seaweed
Extraction
Inflammation
Sulphated polysaccharides
Extraction
Inflammation
Sulphated polysaccharides
Descrición
Review
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Creative Commons Attribution 4.0 International Licence (CC-BY 4.0)
ISSN
1999-4923