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Helicobacter pylori and gastric diseases
https://doi.org/10.18999/nagjms.66.3-4.77
https://doi.org/10.18999/nagjms.66.3-4.77893624b2-4bd2-46ea-bc23-604994d60bcb
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
nj6631.pdf (66.2 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-02-09 | |||||
| タイトル | ||||||
| タイトル | Helicobacter pylori and gastric diseases | |||||
| 言語 | en | |||||
| 著者 |
Goto, Hidemi
× Goto, Hidemi |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ammonia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | IgA | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Lewis antigen | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | tumor necrosis factor | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | polymorphism | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | gastric disease | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Helicobacter pylori (H. pylori) infection is a pathogenic agent of gastric diseases, but their mechanisms are unclear. Effects of ammonia, tumor necrosis factor (TNF), and anti-Lewis autoantibodies induced after H. pylori infection on the development of gastric diseases were investigated. Ammonia disturbed the collagen metabolism in the ulcer base. Soluble TNF receptors regulate the action of TNF. The involvement of anti-Lewis autoantibodies in the development of peptic ulcer might be unlikely. Moreover, H. pylori-specific IgA in gastric juice and TNF α gene polymorphism in persons infected with H. pylori were studied. According to H. pylori-specific IgA titer in gastric juice, persons were divided into two histologically and endoscopically different states of disease. TNFA -857 single nucleotide polymorphism (SNP) may be associated with rugal hyperplastic gastritis and gastric carcinomas without severe atrophy. However, complete elucidation of pathogenic mechanisms of H. pylori-induced gastric diseases requires further research. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.66.3-4.77 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 66, 号 3-4, p. 77-85, 発行日 2003-11 |
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| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/5386 | |||||
| 識別子タイプ | HDL | |||||
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Cite as
Goto, Hidemi, 2003, Helicobacter pylori and gastric diseases: Nagoya University School of Medicine, 77–85 p.
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