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タイトル: | 骨肉腫成分を含む膀胱肉腫様型尿路上皮癌の1例 |
その他のタイトル: | Sarcomatoid Urothelial Carcinoma of the Bladder Including an Osteosarcoma Element |
著者: | 田沼, 光三郎 河合, 弘二 土屋, 春樹 松本, 吉隆 神鳥, 周也 小島, 崇宏 木村, 友和 常樂, 晃 宮崎, 淳 西山, 博之 坂田, 晃子 |
著者名の別形: | Tanuma, Kouzaburou Kawai, Koji Tsuchiya, Haruki Matsumoto, Yoshitaka Kandori, Shuya Kojima, Takahiro Kimura, Tomokazu Joraku, Akira Miyazaki, Jun Nishiyama, Hiroyuki Sakata, Akiko |
キーワード: | Bladder tumor Sarcomatoid variant Urothelial carcinoma Osteosarcoma |
発行日: | 30-Nov-2017 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 63 |
号: | 11 |
開始ページ: | 487 |
終了ページ: | 492 |
抄録: | A 68-year-old Japanese man was referred to Tsukuba University Hospital for bladder cancer treatment. He had undergone a transurethral resection of a bladder tumor (TURBT) at a local hospital, but the pathological specimen did not contain muscle layer. Abdominal computed tomography (CT) and magnetic resonance imaging revealed a 3 cm non-papillary bladder tumor with muscle invasion, but there was no apparent calcification. The patient underwent re-TURBT at our hospital for diagnosis and staging. A non-papillary pedunculated tumor was identified in the bladder dome, and it contained a small papillary part. The non-papillary part was stony hard and difficult to cut with electrocautery, whereas the small papillary part was easily cut. Histologically, the non-papillary part was composed of sarcomatous elements including osteosarcoma, chondrosarcoma, and spindle cell sarcoma. The papillary part was composed of high-grade urothelial carcinoma and spindle cell sarcoma. Muscularis propria was not present in the specimen. Since the staging study with CT was negative for metastases, we performed a total cystectomy with an ileal conduit under the clinical diagnosis of muscle-invasive sarcomatoid urothelial carcinoma. The pathological findings were identical to those of the re-TURBT specimens, and our diagnosis was pTxN0 sarcomatoid urothelial carcinoma. The patient received adjuvant chemotherapy with two courses of gemcitabine and cisplatin. There was neither recurrence nor metastases during the 20-month follow-up. Reports of sarcomatoid urothelial carcinoma of the bladder with an osteosarcoma element are rare, and only eight other cases hane been reported in the Japanese literature. |
著作権等: | 許諾条件により本文は2018/12/01に公開 |
DOI: | 10.14989/ActaUrolJap_63_11_487 |
URI: | http://hdl.handle.net/2433/228198 |
PubMed ID: | 29232802 |
出現コレクション: | Vol.63 No.11 |
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