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Title: | Quality of life and kidney function in older adults: prospective data of the SCOPE study |
Author: | Artzi-Medvedik, Rada Kob, Robert Di Rosa, Mirko Lattanzio, Fabrizia Corsonello, Andrea Yehoshua, Ilian Roller-Wirnsberger, Regina Wirnsberger, Gerhard Mattace-Raso, Francesco Tap, Lisanne Gil, Pedro Formiga Pérez, Francesc Moreno-Gonzalez, Rafael Kostka, Tomasz Guligowska, Agnieszka Ärnlöv, Johan Carlsson, Axel C. Freiberger, Ellen Melzer, Itshak |
Keywords: | Malalties del ronyó Persones grans Qualitat de vida Kidney diseases Older people Quality of life |
Issue Date: | 11-May-2023 |
Publisher: | MDPI |
Abstract: | Abstract: A longitudinal alteration in health-related quality of life (HRQoL) over a two-year period and its association with early-stage chronic kidney disease (CKD) progression was investigated among 1748 older adults (>75 years). HRQoL was measured by the Euro-Quality of Life Visual Analog Scale (EQ-VAS) at baseline and at one and two years after recruitment. A full comprehensive geriatric assessment was performed, including sociodemographic and clinical characteristics, the Geriatric Depression Scale-Short Form (GDS-SF), Short Physical Performance Baery (SPPB), and estimated glomerular filtration rate (eGFR). The association between EQ-VAS decline and covariates was investigated by multivariable analyses. A total of 41% of the participants showed EQ-VAS decline, and 16.3% showed kidney function decline over the two-year follow-up period. Participants with EQ-VAS decline showed an increase in GDS-SF scores and a greater decline in SPPB scores. The logistic regression analyses showed no contribution of a decrease in kidney function on EQVAS decline in the early stages of CKD. However, older adults with a greater GDS-SF score were more likely to present EQ-VAS decline over time, whereas an increase in the SPPB scores was associated with less EQ-VAS decline. This finding should be considered in clinical practice and when HRQoL is used to evaluate health interventions among older adults. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/jcm12123959 |
It is part of: | Journal of Clinical Medicine, 2023, vol. 12 |
URI: | http://hdl.handle.net/2445/199405 |
Related resource: | https://doi.org/10.3390/jcm12123959 |
ISSN: | 2077-0383 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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