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https://hdl.handle.net/10316/105358| Title: | It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling | Authors: | Carvalho, Ana Luísa Fernandes, Dominique |
Issue Date: | Nov-2021 | Publisher: | Public Library of Science | Project: | UIDB/04539/2020 POCI-01-0145- FEDER-28541 POCI-01-0145-FEDER-029452 CENTRO-01-0145- FEDER-000008:BrainHealth2020 “la Caixa” Foundation (ID 100010434) FCT - LCF/PR/HP20/52300003 |
Serial title, monograph or event: | PLoS Biology | Volume: | 19 | Issue: | 11 | Abstract: | Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling. | URI: | https://hdl.handle.net/10316/105358 | ISSN: | 1545-7885 | DOI: | 10.1371/journal.pbio.3001448 | Rights: | openAccess |
| Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais IIIUC - Artigos em Revistas Internacionais |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| It-takes-two-to-tango-Concerted-protein-translation-and-degradation-necessary-for-synaptic-scalingPLoS-Biology.pdf | 1.56 MB | Adobe PDF | View/Open |
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