- Author
-
C. Valkenburg
- Title
- Dentifrice in the prevention of plaque and gingivitis
- Supervisors
- Award date
- 30 November 2021
- Number of pages
- 204
- ISBN
- 9789082605792
- Document type
- PhD thesis
- Faculty
- Faculty of Dentistry (ACTA)
- Abstract
-
Toothpaste scientifically better known as “dentifrice,” is inextricably linked to toothbrushing. But what does it contribute to? Accumulation of dental plaque is the primary cause of the two most common diseases in the oral cavity which is caries and periodontal disease. Daily plaque removal helps to maintain oral health. Toothpaste ingredients may provide additional benefits. The purpose of this thesis was to investigate various aspects of modern toothpastes in relation to toothbrushing to prevent plaque and gingivitis. It evaluates various aspects of the clinical benefit of toothpastes. The research design involved a randomized controlled clinical trial as well as systematic reviews and a meta-review of the literature. At first the contribution of toothpaste to plaque reduction was evaluated. Clinical parameters of plaque, gingivitis and periodontal inflammation were included. Efficacy related to mechanical plaque removal was assessed which showed that toothpaste does not seem to contribute to this. Adding baking soda as an ingredient may improve this aspect. For plaque regrowth inhibition a small but significant effect was established. Active ingredients contribute to this. The clinical trial which evaluated herbal ingredients however failed to observe any beneficial effect. One review evaluated the effect of ‘whitening’ toothpastes and showed that these may reduce extrinsic tooth discoloration. Altogether this thesis makes a strong case that toothpastes provide an adjunctive effect to toothbrushing, not only with the well-established anti-caries effect of fluoridated toothpaste but also with anti-gingivitis properties which promote oral health.
- Other links
- Chapter 2 (original article)
Chapter 8 (original article) - Note
- Please note that chapters 2 and 8 and some decorative images are only available in the printed thesis.
- Persistent Identifier
- https://hdl.handle.net/11245.1/70dfdb36-d5af-412c-8032-423c258f89cf
- Downloads
-
Thesis (complete)
Front matter
Chapter 1: Introduction
Chapter 2: Does dentifrice use help to remove plaque? A systematic review
Chapter 3: Is plaque regrowth inhibited by dentifrice? A systematic review and meta-analysis with trial sequential analysis
Chapter 4: What is the effect of active ingredients in dentifrice on inhibiting the regrowth of overnight plaque? A systematic review
Chapter 5: Plaque control and reduction of gingivitis: The evidence for dentifrices. A meta-review
Chapter 6: Do natural ingredients in a dentifrice contribute to prevention of plaque and gingivitis? A randomized controlled trial
Chapter 7: The efficacy of baking soda dentifrice in controlling plaque and gingivitis. A systematic review
Chapter 8: Whitening dentifrice and tooth surface discoloration. A systematic review and meta-analysis
Chapter 9: Discussion, summary, and conclusion
Chapter 10: Nederlandse samenvatting voor leken
Contributing authors; List of frequently used abbreviations; About the author (Curriculum vitae & PhD portfolio); Dankwoord; Postzegel beschrijvingen
- Supplementary materials
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