Parameters for predicting granulosa cell tumor of the ovary: a single center retrospective comparative study
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Asian Pacific Organization for Cancer Prevention
Access Rights
info:eu-repo/semantics/openAccess
Abstract
Background: To evaluate factors for predicting the granulosa cell tumor of the ovary (GCTO) pre-operatively. Materials and Methods: This retrospective designed study was conducted on 34 women with GCTO as the study group and 76 women with benign ovarian cysts as the control group. Data were recorded from the hospital database and included age, body mass index (BMI), parity, serum estradiol (E2) levels, diameter of the mass, ultrasonographic features, serum CA125 level, risk of malignancy index (RMI), duration of menopause, postoperative histopathology result, and the neutrophil/lymphocyte ratio (NLR). Results: The demographic parameters showed no statistically significant difference between the groups. Preoperative diameter of the mass, CA125, duration of menopause, and neutrophil/lymphocyte ratio were significantly different between the groups. ROC curve analysis demonstrated that diameter of the mass, serum estradiol and Ca125 levels, RMI and NLR may be discriminative factors in predicting GCTO preoperatively. Conclusions: In conclusion, we think that a careful preoperative workshop including diameter of the mass, serum estradiol (E2) and Ca125 levels, RMI and NLR may predict GCTO and may prevent incomplete approaches.
Description
Keywords
E2 and Ca125, Granulosa Cell Tumor, Ovary, Prediction, Risk Factors, RMI and NLR
Journal or Series
Asian Pacific Journal of Cancer Prevention
WoS Q Value
N/A
Scopus Q Value
Q3
Volume
15
Issue
19
Citation
Yeşilyurt, H., Tokmak, A., Güzel, A. İ., Şimşek, H. S., Terzioğlu, S. G., Erkaya, S., Güngör, T. (2014). Parameters for predicting granulosa cell tumor of the ovary: a single center retrospective comparative study. Asian Pacific Organization for Cancer Prevention, 15(19), 8447-8450.
