Discovering functional interaction patterns in protein-protein interaction networks

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2008-06-11

Author

Turanalp, Mehmet E.
Can, Tolga

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Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of genes and/or proteins of an increasing number of organisms. A protein-protein interaction (PPI) network is a particular biological network which represents physical interactions between pairs of proteins of an organism. Major research on PPI networks has focused on understanding the topological organization of PPI networks, evolution of PPI networks and identification of conserved subnetworks across different species, discovery of modules of interaction, use of PPI networks for functional annotation of uncharacterized proteins, and improvement of the accuracy of currently available networks.

Subject Keywords

Biochemistry, Applied Mathematics, Molecular Biology, Structural Biology, Computer Science Applications

URI

https://hdl.handle.net/11511/47646

Journal

BMC BIOINFORMATICS

DOI

https://doi.org/10.1186/1471-2105-9-276

Collections

Department of Computer Engineering, Article

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Citation Formats

M. E. Turanalp and T. Can, “Discovering functional interaction patterns in protein-protein interaction networks,” BMC BIOINFORMATICS, pp. 0–0, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/47646.