Differences in neurovascular coupling in areas with positive and negative BOLD 
signal

Goense, J; Logothetis, NK

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Poster

Differences in neurovascular coupling in areas with positive and negative BOLD signal

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Goense, J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis, NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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https://www.ismrm.org/11/EPF1.htm
(Abstract)

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ISMRM-2011-3600.pdf
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Citation

Goense, J., & Logothetis, N. (2011). Differences in neurovascular coupling in areas with positive and negative BOLD signal. Poster presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-BBF2-A

Abstract

While the dynamics and mechanism of the positive BOLD response have been well studied, much less is known about the mechanism of the negative BOLD response. We studied the properties of the negative BOLD response by comparing the BOLD-, functional CBV- and CBF-responses in regions exhibiting positive and negative BOLD in primary visual cortex (V1) of anesthetized monkeys. Both positive and negative BOLD signals were accompanied by increases in CBV, although CBF was decreased in the unstimulated region.